PDB entry 1cvw

View 1cvw on RCSB PDB site
Description: crystal structure of active site-inhibited human coagulation factor viia (des-gla)
Class: hydrolase/hydrolase inhibitor
Keywords: BLOOD COAGULATION, FACTOR VIIA, SERINE PROTEASE, EGF, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 1999-08-24, released 1999-08-31
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: 0.205
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: coagulation factor viia (heavy chain) (des-gla)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1cvwh_
  • Chain 'J':
    Compound: degr-ck inhibitor (ans-glu-gly-ar7-0qe)
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1CVW (0-4)
  • Chain 'L':
    Compound: coagulation factor viia (light chain) (des-gla)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1cvwl_
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1cvwH (H:)
    ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
    lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
    lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
    sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
    seprpgvllrapfp
    

  • Chain 'J':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1cvwL (L:)
    icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr