PDB entry 1cul

View 1cul on RCSB PDB site
Description: complex of gs-alpha with the catalytic domains of mammalian adenylyl cyclase: complex with 2',5'-dideoxy-adenosine 3'-triphosphate and mg
Class: Lyase/Lyase/Signaling protein
Keywords: complex (lyase/hydrolase), hydrolase, signal transducing protein, cyclase, effector enzyme, lyase/hydrolase complex, lyase/lyase/signaling protein
Deposited on 1999-08-20, released 2001-01-10
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.216
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: type v adenylyl cyclase
    Species: Canis familiaris
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30803
      • engineered (112)
    Domains in SCOP 1.75: d1cula_
  • Chain 'B':
    Compound: type II adenylyl cyclase
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1culb_
  • Chain 'C':
    Compound: guanine nucleotide-binding protein g(s)
    Species: BOS TAURUS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1culc1, d1culc2
  • Heterogens: MG, CL, GSP, FOK, 103, 3PO, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1culA (A:)
memkadinakqedmmfhkiyiqkhdnvsilfadiegftslasqctaqelvmtlnelfarf
dklaaenhclrikilgdcyycvsglpearadhahccvemgmdmieaislvremtgvnvnm
rvgihsgrvhcgvlglrkwqfdvwsndvtlanhmeaggkagrihitkatlsylngdyeve
pgcggernaylkehsietflilrctqkrkeekamiak

    Sequence, based on observed residues (ATOM records): (download) 
    >1culA (A:)
mmfhkiyiqkhdnvsilfadiegftslasqctaqelvmtlnelfarfdklaaenhclrik
ilgdcyycvsglpearadhahccvemgmdmieaislvremtgvnvnmrvgihsgrvhcgv
lglrkwqfdvwsndvtlanhmeaggkagrihitkatlsylngdyevepgcggernaylke
hsietflil

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1culB (B:)
neelyhqsydcvcvmfasipdfkefytesdvnkegleclrllneiiadfddllskpkfsg
vekiktigstymaatglsaipsqehaqeperqymhigtmvefayalvgkldainkhsfnd
fklrvginhgpviagvigaqkpqydiwgntvnvasrmdstgvldkiqvteetslilqtlg
ytctcrgiinvkgkgdlktyfvntemsr

    Sequence, based on observed residues (ATOM records): (download) 
    >1culB (B:)
yhqsydcvcvmfasipdfkefytesdvnkegleclrllneiiadfddllskpkfsgveki
ktigstymaatglsaerqymhigtmvefayalvgkldainkhsfndfklrvginhgpvia
gvigaqkpqydiwgntvnvasrmdstgvldkiqvteetslilqtlgytctcrgiinvkgk
gdlktyfvnt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1culC (C:)
mgclgnsktedqrneekaqreankkiekqlqkdkqvyrathrllllgagesgkstivkqm
rilhvngfngdgekatkvqdiknnlkeaietivaamsnlvppvelanpenqfrvdyilsv
mnvpdfdfppefyehakalwedegvracyersneyqlidcaqyfldkidvikqddyvpsd
qdllrcrvltsgifetkfqvdkvnfhmfdvggqrderrkwiqcfndvtaiifvvasssyn
mvirednqtnrlqealnlfksiwnnrwlrtisvilflnkqdllaekvlagkskiedyfpe
faryttpedatpepgedprvtrakyfirdeflristasgdgrhycyphftcavdtenirr
vfndcrdiiqrmhlrqyell

    Sequence, based on observed residues (ATOM records): (download) 
    >1culC (C:)
athrllllgagesgkstivkqmrilhvgekatkvqdiknnlkeaietivaamsnlvppve
lanpenqfrvdyilsvmnvpdfdfppefyehakalwedegvracyersneyqlidcaqyf
ldkidvikqddyvpsdqdllrcrvltsgifetkfqvdkvnfhmfdvggqrderrkwiqcf
ndvtaiifvvasssynmvirednqtnrlqealnlfksiwnnrwlrtisvilflnkqdlla
ekvlagkskiedyfpefaryttpedatpepgedprvtrakyfirdeflristasgdgrhy
cyphftcavdtenirrvfndcrdiiqrm