PDB entry 1cu4

View 1cu4 on RCSB PDB site
Description: crystal structure of the anti-prion fab 3f4 in complex with its peptide epitope
Class: immune system
Keywords: immunoglobulin fold, immune system
Deposited on 1999-08-20, released 2000-04-17
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.159
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1CU4 (Start-216)
    Domains in SCOPe 2.05: d1cu4h1, d1cu4h2
  • Chain 'L':
    Compound: Fab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1CU4 (0-218)
    Domains in SCOPe 2.05: d1cu4l1, d1cu4l2
  • Chain 'P':
    Compound: recognition peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1CU4 (0-9)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1cu4H (H:)
kvklqqsgaelvrsgasvklsctasgfnikdyyiqwvkqrpeqglewigwidpengnsey
aprfqgkatmtadtlsntaylqlssltsedtavyycnadlhdywgqgttltvssakttap
svyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsdlytlss
svtvtsstwpsqsitcnvahpasstkvdkkieprvts

    Sequence, based on observed residues (ATOM records): (download) 
    >1cu4H (H:)
klqqsgaelvrsgasvklsctasgfnikdyyiqwvkqrpeqglewigwidpengnseyap
rfqgkatmtadtlsntaylqlssltsedtavyycnadlhdywgqgttltvssakttapsv
yplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsdlytlsssv
tvtsstwpsqsitcnvahpasstkvdkkieprvts

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1cu4L (L:)
dvvmtqtplslsvtigqpasisckssqslldsdgktyliwvfqrpgqspkrliflvskrd
sgvpdrftgsgsgtdftlkisrveaedvgvyycwqgthfphtvgggtkleiaradaaptv
sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
sstltltkdeyerhnsytceathktstspivksfnrnec

  • Chain 'P':
    No sequence available.