PDB entry 1cse

View 1cse on RCSB PDB site
Description: the high-resolution x-ray crystal structure of the complex formed between subtilisin carlsberg and eglin c, an elastase inhibitor from the leech hirudo medicinalis. structural analysis, subtilisin structure and interface geometry
Class: complex(serine proteinase-inhibitor)
Keywords: complex(serine proteinase-inhibitor)
Deposited on 1988-06-03, released 1988-07-16
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.2 Å
R-factor: 0.178
AEROSPACI score: 0.79 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: subtilisin carlsberg
    Species: Bacillus subtilis [TaxId:1423]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00780 (0-273)
      • conflict (101)
      • conflict (127)
      • conflict (156)
      • conflict (159)
      • conflict (210)
    Domains in SCOPe 2.04: d1csee_
  • Chain 'I':
    Compound: eglin c
    Species: Hirudo medicinalis [TaxId:6421]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01051 (Start-69)
      • conflict (32)
    Domains in SCOPe 2.04: d1csei_
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1cseE (E:)
aqtvpygiplikadkvqaqgfkganvkvavldtgiqashpdlnvvggasfvageayntdg
nghgthvagtvaaldnttgvlgvapsvslyavkvlnssgsgsysgivsgiewattngmdv
inmslggasgstamkqavdnayargvvvvaaagnsgnsgstntigypakydsviavgavd
snsnrasfssvgaelevmapgagvystyptntyatlngtsmasphvagaaalilskhpnl
sasqvrnrlsstatylgssfyygkglinveaaaq

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1cseI (I:)
tefgselksfpevvgktvdqareyftlhypqynvyflpegspvtldlrynrvrvfynpgt
nvvnhvphvg

    Sequence, based on observed residues (ATOM records): (download) 
    >1cseI (I:)
ksfpevvgktvdqareyftlhypqynvyflpegspvtldlrynrvrvfynpgtnvvnhvp
hvg