PDB entry 1cpj
View 1cpj on RCSB PDB site
Description: crystal structures of recombinant rat cathepsin b and a cathepsin b-inhibitor complex: implications for structure-based inhibitor design
Class: hydrolase
Keywords: thiol protease, hydrolase
Deposited on
1995-07-17, released
1995-12-07
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-11.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.175
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cathepsin b
Species: Rattus norvegicus [TaxId:10116]
Gene: CDNA
Database cross-references and differences (RAF-indexed):
- Uniprot P00787
- engineered (120)
- cloning artifact (228)
Domains in SCOPe 2.08: d1cpja_ - Chain 'B':
Compound: cathepsin b
Species: Rattus norvegicus [TaxId:10116]
Gene: CDNA
Database cross-references and differences (RAF-indexed):
- Uniprot P00787
- engineered (120)
- cloning artifact (228)
Domains in SCOPe 2.08: d1cpjb_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1cpjA (A:)
fsedinlpesfdareqwsncptiaqirdqgscgscwafgaveamsdricihtngrvnvev
saedlltccgiqcgdgcnggypsgawnfwtrkglvsggvynshigclpytippcehhvng
arppctgegdtpkcnkmceagystsykedkhygytsysvsdsekeimaeiykngpvegaf
tvfsdfltyksgvykheagdvmgghairilgwgiengvpywlvanswnadwgdngffkil
rgenhcgieseivagiprtq
Sequence, based on observed residues (ATOM records): (download)
>1cpjA (A:)
lpesfdareqwsncptiaqirdqgscgscwafgaveamsdricihtngrvnvevsaedll
tccgiqcgdgcnggypsgawnfwtrkglvsggvynshigclpytippcehhvngarppct
gegdtpkcnkmceagystsykedkhygytsysvsdsekeimaeiykngpvegaftvfsdf
ltyksgvykheagdvmgghairilgwgiengvpywlvanswnadwgdngffkilrgenhc
gieseivagiprt
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1cpjB (B:)
fsedinlpesfdareqwsncptiaqirdqgscgscwafgaveamsdricihtngrvnvev
saedlltccgiqcgdgcnggypsgawnfwtrkglvsggvynshigclpytippcehhvng
arppctgegdtpkcnkmceagystsykedkhygytsysvsdsekeimaeiykngpvegaf
tvfsdfltyksgvykheagdvmgghairilgwgiengvpywlvanswnadwgdngffkil
rgenhcgieseivagiprtq
Sequence, based on observed residues (ATOM records): (download)
>1cpjB (B:)
lpesfdareqwsncptiaqirdqgscgscwafgaveamsdricihtngrvnvevsaedll
tccgiqcgdgcnggypsgawnfwtrkglvsggvynshigclpytippcehhvngarppct
gegdtpkcnkmceagystsykedkhygytsysvsdsekeimaeiykngpvegaftvfsdf
ltyksgvykheagdvmgghairilgwgiengvpywlvanswnadwgdngffkilrgenhc
gieseivagiprt