PDB entry 1co3

View 1co3 on RCSB PDB site
Description: crystal structure of the nadp+ dependent aldehyde dehydrogenase from vibrio harveyi. structural comparison with nad+ dependent enzymes.
Class: oxidoreductase
Keywords: aldehyde dehydrogenase, nadp+ specificity, non classical nucleotide binding domain, thiohemiacetal intermediate, vibrio harveyi
Deposited on 1999-06-02, released 1999-11-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2000-05-24, with a file datestamp of 2007-04-25.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.205
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (aldehyde dehydrogenase)
    Species: VIBRIO HARVEYI
    Gene: ALDH
    Database cross-references and differences (RAF-indexed):
    • GB U39638
      • conflict (440)
    Domains in SCOPe 2.08: d1co3a_
  • Chain 'B':
    Compound: protein (aldehyde dehydrogenase)
    Species: VIBRIO HARVEYI
    Gene: ALDH
    Database cross-references and differences (RAF-indexed):
    • GB U39638
      • conflict (440)
    Domains in SCOPe 2.08: d1co3b_
  • Chain 'C':
    Compound: protein (aldehyde dehydrogenase)
    Species: VIBRIO HARVEYI
    Gene: ALDH
    Database cross-references and differences (RAF-indexed):
    • GB U39638
      • conflict (440)
    Domains in SCOPe 2.08: d1co3c_
  • Chain 'D':
    Compound: protein (aldehyde dehydrogenase)
    Species: VIBRIO HARVEYI
    Gene: ALDH
    Database cross-references and differences (RAF-indexed):
    • GB U39638
      • conflict (440)
    Domains in SCOPe 2.08: d1co3d_
  • Heterogens: NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1co3A (A:)
mnpqtdnvfyatnaftgealplafpvhtevevnqaataaakvardfrrlnnskrasllrt
iaselearsddiiarahletalpevrltgeiartanqlrlfadvvnsgsyhqaildtpnp
traplpkpdirrqqialgpvavfgasnfplafsaaggdtasalaagcpvivkghtahpgt
sqivaecieqalkqeqlpqaiftllqgnqralgqalvshpeikavgftgsvgggralfnl
aherpepipfygelgainptfifpsamrakadladqfvasmtmgcgqfctkpgvvfalnt
petqafietaqslirqqspstlltpgirdsyqsqvvsrgsddgidvtfsqaespcvasal
fvtssenwrkhpaweeeifgpqslivvcenvadmlslsemlagsltatihateedypqvs
qliprleeiagrlvfngwptevevgyamvhggpypasthsastsvgaeaihrwlrpvayq
alpesllpdslkaenpleiaravdgkaahs

    Sequence, based on observed residues (ATOM records): (download) 
    >1co3A (A:)
qtdnvfyatnaftgealplafpvhtevevnqaataaakvardfrrlnnskrasllrtias
elearsddiiarahletalpevrltgeiartanqlrlfadvvnsgsyhqaildtpnptra
plpkpdirrqqialgpvavfgasnfplafsaaggdtasalaagcpvivkghtahpgtsqi
vaecieqalkqeqlpqaiftllqgnqralgqalvshpeikavgftgsvgggralfnlahe
rpepipfygelgainptfifpsamrakadladqfvasmtmgcgqfctkpgvvfalntpet
qafietaqslirqqspstlltpgirdsyqsqvvsrgsddgidvtfsqaespcvasalfvt
ssenwrkhpaweeeifgpqslivvcenvadmlslsemlagsltatihateedypqvsqli
prleeiagrlvfngwptevevgyamvhggpypasthsastsvgaeaihrwlrpvayqalp
esllpdslkaenpleiaravdgkaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1co3B (B:)
mnpqtdnvfyatnaftgealplafpvhtevevnqaataaakvardfrrlnnskrasllrt
iaselearsddiiarahletalpevrltgeiartanqlrlfadvvnsgsyhqaildtpnp
traplpkpdirrqqialgpvavfgasnfplafsaaggdtasalaagcpvivkghtahpgt
sqivaecieqalkqeqlpqaiftllqgnqralgqalvshpeikavgftgsvgggralfnl
aherpepipfygelgainptfifpsamrakadladqfvasmtmgcgqfctkpgvvfalnt
petqafietaqslirqqspstlltpgirdsyqsqvvsrgsddgidvtfsqaespcvasal
fvtssenwrkhpaweeeifgpqslivvcenvadmlslsemlagsltatihateedypqvs
qliprleeiagrlvfngwptevevgyamvhggpypasthsastsvgaeaihrwlrpvayq
alpesllpdslkaenpleiaravdgkaahs

    Sequence, based on observed residues (ATOM records): (download) 
    >1co3B (B:)
nvfyatnaftgealplafpvhtevevnqaataaakvardfrrlnnskrasllrtiasele
arsddiiarahletalpevrltgeiartanqlrlfadvvnsgsyhqaildtpnptraplp
kpdirrqqialgpvavfgasnfplafsaaggdtasalaagcpvivkghtahpgtsqivae
cieqalkqeqlpqaiftllqgnqralgqalvshpeikavgftgsvgggralfnlaherpe
pipfygelgainptfifpsamrakadladqfvasmtmgcgqfctkpgvvfalntpetqaf
ietaqslirqqspstlltpgirdsyqsqvvsrgsddgidvtfsqaespcvasalfvtsse
nwrkhpaweeeifgpqslivvcenvadmlslsemlagsltatihateedypqvsqliprl
eeiagrlvfngwptevevgyamvhggpypasthsastsvgaeaihrwlrpvayqalpesl
lpdslkaenpleiaravdgkaa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1co3C (C:)
mnpqtdnvfyatnaftgealplafpvhtevevnqaataaakvardfrrlnnskrasllrt
iaselearsddiiarahletalpevrltgeiartanqlrlfadvvnsgsyhqaildtpnp
traplpkpdirrqqialgpvavfgasnfplafsaaggdtasalaagcpvivkghtahpgt
sqivaecieqalkqeqlpqaiftllqgnqralgqalvshpeikavgftgsvgggralfnl
aherpepipfygelgainptfifpsamrakadladqfvasmtmgcgqfctkpgvvfalnt
petqafietaqslirqqspstlltpgirdsyqsqvvsrgsddgidvtfsqaespcvasal
fvtssenwrkhpaweeeifgpqslivvcenvadmlslsemlagsltatihateedypqvs
qliprleeiagrlvfngwptevevgyamvhggpypasthsastsvgaeaihrwlrpvayq
alpesllpdslkaenpleiaravdgkaahs

    Sequence, based on observed residues (ATOM records): (download) 
    >1co3C (C:)
nvfyatnaftgealplafpvhtevevnqaataaakvardfrrlnnskrasllrtiasele
arsddiiarahletalpevrltgeiartanqlrlfadvvnsgsyhqaildtpnptraplp
kpdirrqqialgpvavfgasnfplafsaaggdtasalaagcpvivkghtahpgtsqivae
cieqalkqeqlpqaiftllqgnqralgqalvshpeikavgftgsvgggralfnlaherpe
pipfygelgainptfifpsamrakadladqfvasmtmgcgqfctkpgvvfalntpetqaf
ietaqslirqqspstlltpgirdsyqsqvvsrgsddgidvtfsqaespcvasalfvtsse
nwrkhpaweeeifgpqslivvcenvadmlslsemlagsltatihateedypqvsqliprl
eeiagrlvfngwptevevgyamvhggpypasthsastsvgaeaihrwlrpvayqalpesl
lpdslkaenpleiaravdgkaa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1co3D (D:)
mnpqtdnvfyatnaftgealplafpvhtevevnqaataaakvardfrrlnnskrasllrt
iaselearsddiiarahletalpevrltgeiartanqlrlfadvvnsgsyhqaildtpnp
traplpkpdirrqqialgpvavfgasnfplafsaaggdtasalaagcpvivkghtahpgt
sqivaecieqalkqeqlpqaiftllqgnqralgqalvshpeikavgftgsvgggralfnl
aherpepipfygelgainptfifpsamrakadladqfvasmtmgcgqfctkpgvvfalnt
petqafietaqslirqqspstlltpgirdsyqsqvvsrgsddgidvtfsqaespcvasal
fvtssenwrkhpaweeeifgpqslivvcenvadmlslsemlagsltatihateedypqvs
qliprleeiagrlvfngwptevevgyamvhggpypasthsastsvgaeaihrwlrpvayq
alpesllpdslkaenpleiaravdgkaahs

    Sequence, based on observed residues (ATOM records): (download) 
    >1co3D (D:)
nvfyatnaftgealplafpvhtevevnqaataaakvardfrrlnnskrasllrtiasele
arsddiiarahletalpevrltgeiartanqlrlfadvvnsgsyhqaildtpnptraplp
kpdirrqqialgpvavfgasnfplafsaaggdtasalaagcpvivkghtahpgtsqivae
cieqalkqeqlpqaiftllqgnqralgqalvshpeikavgftgsvgggralfnlaherpe
pipfygelgainptfifpsamrakadladqfvasmtmgcgqfctkpgvvfalntpetqaf
ietaqslirqqspstlltpgirdsyqsqvvsrgsddgidvtfsqaespcvasalfvtsse
nwrkhpaweeeifgpqslivvcenvadmlslsemlagsltatihateedypqvsqliprl
eeiagrlvfngwptevevgyamvhggpypasthsastsvgaeaihrwlrpvayqalpesl
lpdslkaenpleiaravdgkaa