PDB entry 1cju

View 1cju on RCSB PDB site
Description: complex of gs-alpha with the catalytic domains of mammalian adenylyl cyclase: complex with beta-l-2',3'-dideoxyatp and mg
Class: lyase/lyase/signaling protein
Keywords: complex (lyase/hydrolase), hydrolase, signal transducing protein, cyclase, effector enzyme
Deposited on 1999-04-16, released 1999-08-31
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.222
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenylate cyclase, type v
    Species: Canis familiaris
    Gene: ADENYLYL CYCLASE TYPE V
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30803
      • engineered (112)
    Domains in SCOP 1.73: d1cjua_
  • Chain 'B':
    Compound: adenylate cyclase, type II
    Species: Rattus norvegicus
    Gene: ADENYLYL CYCLASE TYPE II
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1cjub_
  • Chain 'C':
    Compound: guanine nucleotide-binding protein g(s)
    Species: BOS TAURUS
    Gene: GNAS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1cjuc1, d1cjuc2
  • Heterogens: MG, CL, GSP, FOK, DAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1cjuA (A:)
memkadinakqedmmfhkiyiqkhdnvsilfadiegftslasqctaqelvmtlnelfarf
dklaaenhclrikilgdcyycvsglpearadhahccvemgmdmieaislvremtgvnvnm
rvgihsgrvhcgvlglrkwqfdvwsndvtlanhmeaggkagrihitkatlsylngdyeve
pgcggernaylkehsietflilrctqkrkeekamiak

    Sequence, based on observed residues (ATOM records): (download) 
    >1cjuA (A:)
mmfhkiyiqkhdnvsilfadiegftslasqctaqelvmtlnelfarfdklaaenhclrik
ilgdcyycvsglpearadhahccvemgmdmieaislvremtgvnvnmrvgihsgrvhcgv
lglrkwqfdvwsndvtlanhmeaggkagrihitkatlsylngdyevepgcggernaylke
hsietflil

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1cjuB (B:)
rslkneelyhqsydcvcvmfasipdfkefytesdvnkegleclrllneiiadfddllskp
kfsgvekiktigstymaatglsaipsqehaqeperqymhigtmvefayalvgkldainkh
sfndfklrvginhgpviagvigaqkpqydiwgntvnvasrmdstgvldkiqvteetslil
qtlgytctcrgiinvkgkgdlktyfvntemsr

    Sequence, based on observed residues (ATOM records): (download) 
    >1cjuB (B:)
yhqsydcvcvmfasipdfkefytesdvnkegleclrllneiiadfddllskpkfsgveki
ktigstymaatglsarqymhigtmvefayalvgkldainkhsfndfklrvginhgpviag
vigaqkpqydiwgntvnvasrmdstgvldkiqvteetslilqtlgytctcrgiinvkgkg
dlktyfvnt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1cjuC (C:)
mgclgnsktedqrneekaqreankkiekqlqkdkqvyrathrllllgagesgkstivkqm
rilhvngfnggeggeedpnaksnsdgekatkvqdiknnlkeaietivaamsnlvppvela
npenqfrvdyilsvmnvpdfdfppefyehakalwedegvracyersneyqlidcaqyfld
kidvikqddyvpsdqdllrcrvltsgifetkfqvdkvnfhmfdvggqrderrkwiqcfnd
vtaiifvvasssynmvirednqtnrlqealnlfksiwnnrwlrtisvilflnkqdllaek
vlagkskiedyfpefaryttpedatpepgedprvtrakyfirdeflristasgdgrhycy
phftcavdtenirrvfndcrdiiqrmhlrqyellgghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1cjuC (C:)
athrllllgagesgkstivkqmrilhvngekatkvqdiknnlkeaietivaamsnlvppv
elanpenqfrvdyilsvmnvpdfdfppefyehakalwedegvracyersneyqlidcaqy
fldkidvikqddyvpsdqdllrcrvltsgifetkfqvdkvnfhmfdvggqrderrkwiqc
fndvtaiifvvasssynmvirednqtnrlqealnlfksiwnnrwlrtisvilflnkqdll
aekvlagkskiedyfpefaryttpedatpepgedprvtrakyfirdeflristasgdgrh
ycyphftcavdtenirrvfndcrdiiqrmhl