PDB entry 1cjk

View 1cjk on RCSB PDB site
Description: complex of gs-alpha with the catalytic domains of mammalian adenylyl cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp), mg, and mn
Class: lyase/lyase/signaling protein
Keywords: complex (lyase-hydrolase), hydrolase, signal transducing protein, cyclase, effector enzyme, lyase-lyase-signaling protein complex
Deposited on 1999-04-16, released 1999-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenylate cyclase, type v
    Species: Canis lupus [TaxId:9615]
    Gene: ADENYLYL CYCLASE TYPE V
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30803
      • engineered (112)
    Domains in SCOPe 2.08: d1cjka_
  • Chain 'B':
    Compound: adenylate cyclase, type II
    Species: Rattus norvegicus [TaxId:10116]
    Gene: ADENYLYL CYCLASE TYPE II
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1cjkb_
  • Chain 'C':
    Compound: guanine nucleotide-binding protein g(s)
    Species: Bos taurus [TaxId:9913]
    Gene: GNAS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1cjkc1, d1cjkc2
  • Heterogens: MG, MN, FOK, TAT, MES, CL, GSP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1cjkA (A:)
memkadinakqedmmfhkiyiqkhdnvsilfadiegftslasqctaqelvmtlnelfarf
dklaaenhclrikilgdcyycvsglpearadhahccvemgmdmieaislvremtgvnvnm
rvgihsgrvhcgvlglrkwqfdvwsndvtlanhmeaggkagrihitkatlsylngdyeve
pgcggernaylkehsietflilrctqkrkeekamiak

    Sequence, based on observed residues (ATOM records): (download) 
    >1cjkA (A:)
mmfhkiyiqkhdnvsilfadiegftslasqctaqelvmtlnelfarfdklaaenhclrik
ilgdcyycvsglpearadhahccvemgmdmieaislvremtgvnvnmrvgihsgrvhcgv
lglrkwqfdvwsndvtlanhmeaggkagrihitkatlsylngdyevepgcggernaylke
hsietflil

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1cjkB (B:)
rslkneelyhqsydcvcvmfasipdfkefytesdvnkegleclrllneiiadfddllskp
kfsgvekiktigstymaatglsaipsqehaqeperqymhigtmvefayalvgkldainkh
sfndfklrvginhgpviagvigaqkpqydiwgntvnvasrmdstgvldkiqvteetslil
qtlgytctcrgiinvkgkgdlktyfvntemsr

    Sequence, based on observed residues (ATOM records): (download) 
    >1cjkB (B:)
lyhqsydcvcvmfasipdfkefytesdvnkegleclrllneiiadfddllskpkfsgvek
iktigstymaatglsarqymhigtmvefayalvgkldainkhsfndfklrvginhgpvia
gvigaqkpqydiwgntvnvasrmdstgvldkiqvteetslilqtlgytctcrgiinvkgk
gdlktyfvnt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1cjkC (C:)
mgclgnsktedqrneekaqreankkiekqlqkdkqvyrathrllllgagesgkstivkqm
rilhvngfnggeggeedpnaksnsdgekatkvqdiknnlkeaietivaamsnlvppvela
npenqfrvdyilsvmnvpdfdfppefyehakalwedegvracyersneyqlidcaqyfld
kidvikqddyvpsdqdllrcrvltsgifetkfqvdkvnfhmfdvggqrderrkwiqcfnd
vtaiifvvasssynmvirednqtnrlqealnlfksiwnnrwlrtisvilflnkqdllaek
vlagkskiedyfpefaryttpedatpepgedprvtrakyfirdeflristasgdgrhycy
phftcavdtenirrvfndcrdiiqrmhlrqyellgghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1cjkC (C:)
athrllllgagesgkstivkqmrilhvgekatkvqdiknnlkeaietivaamsnlvppve
lanpenqfrvdyilsvmnvpdfdfppefyehakalwedegvracyersneyqlidcaqyf
ldkidvikqddyvpsdqdllrcrvltsgifetkfqvdkvnfhmfdvggqrderrkwiqcf
ndvtaiifvvasssynmvirednqtnrlqealnlfksiwnnrwlrtisvilflnkqdlla
ekvlagkskiedyfpefaryttpedatpepgedprvtrakyfirdeflristasgdgrhy
cyphftcavdtenirrvfndcrdiiqrmhl