PDB entry 1cet
View 1cet on RCSB PDB site
Description: chloroquine binds in the cofactor binding site of plasmodium falciparum lactate dehydrogenase.
Class: oxidoreductase
Keywords: oxidoreductase, tricarboxylic acid cycle, inhibitor
Deposited on
1999-03-10, released
1999-03-19
The last revision prior to the SCOPe 2.07 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.154
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein (l-lactate dehydrogenase)
Species: Plasmodium falciparum [TaxId:5833]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d1ceta1, d1ceta2 - Heterogens: CLQ, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1cetA (A:)
mapkakivlvgsgmiggvmatlivqknlgdvvlfdivknmphgkaldtshtnvmaysnck
vsgsntyddlagsdvvivtagftkapgksdkewnrldllplnnkimieigghikkncpna
fiivvtnpvdvmvqllhqhsgvpknkiiglggvldtsrlkyyisqklnvcprdvnahivg
ahgnkmvllkryitvggiplqefinnklisdaeleaifdrtvntaleivnlhaspyvapa
aaiiemaesylkdlkkvlicstllegqyghsdifggtpvvlgangveqvielqlnseeka
kfdeaiaetkrmkala
Sequence, based on observed residues (ATOM records): (download)
>1cetA (A:)
apkakivlvgsgmiggvmatlivqknlgdvvlfdivknmphgkaldtshtnvmaysnckv
sgsntyddlagsdvvivtagftnrldllplnnkimieigghikkncpnafiivvtnpvdv
mvqllhqhsgvpknkiiglggvldtsrlkyyisqklnvcprdvnahivgahgnkmvllkr
yitvggiplqefinnklisdaeleaifdrtvntaleivnlhaspyvapaaaiiemaesyl
kdlkkvlicstllegqyghsdifggtpvvlgangveqvielqlnseekakfdeaiaetkr
mkala