PDB entry 1ca0

View 1ca0 on RCSB PDB site
Description: bovine chymotrypsin complexed to appi
Class: complex (serine protease/inhibitor)
Keywords: serine protease, inhibitor, protease-substrate interactions, complex (serine protease/inhibitor)
Deposited on 1997-01-23, released 1997-07-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.215
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: bovine chymotrypsin
  Species: Bos taurus [TaxId:9913]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00766 (0-End)
  Domains in SCOPe 2.08: d1ca0.1
• Chain 'B':
  Compound: bovine chymotrypsin
  Species: Bos taurus [TaxId:9913]
  Gene: A4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00766 (0-130)
  Domains in SCOPe 2.08: d1ca0.1
• Chain 'C':
  Compound: bovine chymotrypsin
  Species: Bos taurus [TaxId:9913]
  Gene: A4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00766 (0-96)
  Domains in SCOPe 2.08: d1ca0.1
• Chain 'D':
  Compound: protease inhibitor domain of alzheimer's amyloid beta-protein precursor
  Species: Homo sapiens [TaxId:9606]
  Gene: A4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P05067 (0-53)
  Domains in SCOPe 2.08: d1ca0d_
• Chain 'F':
  Compound: bovine chymotrypsin
  Species: Bos taurus [TaxId:9913]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00766 (0-End)
  Domains in SCOPe 2.08: d1ca0.2
• Chain 'G':
  Compound: bovine chymotrypsin
  Species: Bos taurus [TaxId:9913]
  Gene: A4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00766 (0-130)
  Domains in SCOPe 2.08: d1ca0.2
• Chain 'H':
  Compound: bovine chymotrypsin
  Species: Bos taurus [TaxId:9913]
  Gene: A4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00766 (0-96)
  Domains in SCOPe 2.08: d1ca0.2
• Chain 'I':
  Compound: protease inhibitor domain of alzheimer's amyloid beta-protein precursor
  Species: Homo sapiens [TaxId:9606]
  Gene: A4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P05067 (0-53)
  Domains in SCOPe 2.08: d1ca0i_
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >1ca0A (A:)
  cgvpaiqpvlsgl
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >1ca0A (A:)
  cgvpaiqpvls
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ca0B (B:)
  ivngeeavpgswpwqvslqdktgfhfcggslinenwvvtaahcgvttsdvvvagefdqgs
  ssekiqklkiakvfknskynsltinnditllklstaasfsqtvsavclpsasddfaagtt
  cvttgwgltry
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ca0C (C:)
  antpdrlqqaslpllsntnckkywgtkikdamicagasgvsscmgdsggplvckkngawt
  lvgivswgsstcststpgvyarvtalvnwvqqtlaan
  

  
  
• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ca0D (D:)
  evcseqaetgpcramisrwyfdvtegkcapffyggcggnrnnfdteeycmavcg
  

  
  
• Chain 'F':
  Sequence, based on SEQRES records: (download)
  

  >1ca0F (F:)
  cgvpaiqpvlsgl
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >1ca0F (F:)
  cgvpaiqpvls
  

  
  
• Chain 'G':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ca0G (G:)
  ivngeeavpgswpwqvslqdktgfhfcggslinenwvvtaahcgvttsdvvvagefdqgs
  ssekiqklkiakvfknskynsltinnditllklstaasfsqtvsavclpsasddfaagtt
  cvttgwgltry
  

  
  
• Chain 'H':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ca0H (H:)
  antpdrlqqaslpllsntnckkywgtkikdamicagasgvsscmgdsggplvckkngawt
  lvgivswgsstcststpgvyarvtalvnwvqqtlaan
  

  
  
• Chain 'I':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ca0I (I:)
  evcseqaetgpcramisrwyfdvtegkcapffyggcggnrnnfdteeycmavcg