PDB entry 1c8m

View 1c8m on RCSB PDB site
Description: refined crystal structure of human rhinovirus 16 complexed with vp63843 (pleconaril), an anti-picornaviral drug currently in clinical trials
Class: virus
Keywords: RHINOVIRUS COAT PROTEIN, HUMAN RHINOVIRUS 16, ANTIVIRAL COMPOUND, DRUG, WIN COMPOUND, Icosahedral virus, Virus
Deposited on 2000-05-26, released 2000-11-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: human rhinovirus 16 coat protein
    Species: Human rhinovirus 16 [TaxId:31708]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1c8m1_
  • Chain '2':
    Compound: human rhinovirus 16 coat protein
    Species: Human rhinovirus 16 [TaxId:31708]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1c8m.1
  • Chain '3':
    Compound: human rhinovirus 16 coat protein
    Species: Human rhinovirus 16 [TaxId:31708]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1c8m3_
  • Chain '4':
    Compound: human rhinovirus 16 coat protein
    Species: Human rhinovirus 16 [TaxId:31708]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q82122 (0-End)
      • conflict (23)
    Domains in SCOPe 2.08: d1c8m.1
  • Heterogens: ZN, W11, HOH

PDB Chain Sequences:

  • Chain '1':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1c8m1 (1:)
npveryvdevlnevlvvpninqshpttsnaapvldaaetghtnkiqpedtietryvqssq
tldemsvesflgrsgcihesvldivdnyndqsftkwninlqemaqirrkfemftyarfds
eitmvpsvaakdghighivmqymyvppgapipttrddyawqsgtnasvfwqhgqpfprfs
lpflsiasayymfydgydgdtyksrygtvvtndmgtlcsrivtseqlhkvkvvtriyhka
khtkawcprppravqyshthttnyklssevhndvairprtnlttv

  • Chain '2':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1c8m2 (2:)
sdriiqitrgdstitsqdvanavvgygvwphyltpqdataidkptqpdtssnrfytldsk
mwnstskgwwwklpdalkdmgifgenmfyhflgrsgytvhvqcnaskfhqgtllvvmipe
hqlatvnkgnvnagykythpgeagrevgtqvenekqpsddnwlnfdgtllgnllifphqf
inlrsnnsatlivpyvnavpmdsmvrhnnwslviipvcqlqsnnisnivpitvsispmca
efsgaraktvvq

  • Chain '3':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1c8m3 (3:)
glpvyvtpgsgqfmttddmqspcalpwyhptkeifipgevknliemcqvdtlipinstqs
nignvsmytvtlspqtklaeeifaikvdiashplattligeiasyfthwtgslrfsfmfc
gtanttlkvllaytppgigkprsrkeamlgthvvwdvglqstvslvvpwisasqyrfttp
dtyssagyitcwyqtnfvvppntpntaemlcfvsgckdfclrmardtdlhkqtgpitq

  • Chain '4':
    Sequence, based on SEQRES records: (download) 
    >1c8m4 (4:)
gaqvsrqnvgthstqnmvsngssinyfninyfkdaassgasrldfsqdpskftdpvkdvl
ekgiptlqspsveacgy

    Sequence, based on observed residues (ATOM records): (download) 
    >1c8m4 (4:)
gaqvsrqsinyfninyfkdaassgasrld