PDB entry 1c8m
View 1c8m on RCSB PDB site
Description: refined crystal structure of human rhinovirus 16 complexed with vp63843 (pleconaril), an anti-picornaviral drug currently in clinical trials
Class: virus
Keywords: RHINOVIRUS COAT PROTEIN, HUMAN RHINOVIRUS 16, ANTIVIRAL COMPOUND, DRUG, WIN COMPOUND, Icosahedral virus, Virus
Deposited on
2000-05-26, released
2000-11-22
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-04, with a file datestamp of
2017-09-29.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16
(click here for full SPACI score report)
Chains and heterogens:
- Chain '1':
Compound: human rhinovirus 16 coat protein
Species: Human rhinovirus 16 [TaxId:31708]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1c8m1_ - Chain '2':
Compound: human rhinovirus 16 coat protein
Species: Human rhinovirus 16 [TaxId:31708]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1c8m.1 - Chain '3':
Compound: human rhinovirus 16 coat protein
Species: Human rhinovirus 16 [TaxId:31708]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1c8m3_ - Chain '4':
Compound: human rhinovirus 16 coat protein
Species: Human rhinovirus 16 [TaxId:31708]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1c8m.1 - Heterogens: ZN, W11, HOH
PDB Chain Sequences:
- Chain '1':
Sequence; same for both SEQRES and ATOM records: (download)
>1c8m1 (1:)
npveryvdevlnevlvvpninqshpttsnaapvldaaetghtnkiqpedtietryvqssq
tldemsvesflgrsgcihesvldivdnyndqsftkwninlqemaqirrkfemftyarfds
eitmvpsvaakdghighivmqymyvppgapipttrddyawqsgtnasvfwqhgqpfprfs
lpflsiasayymfydgydgdtyksrygtvvtndmgtlcsrivtseqlhkvkvvtriyhka
khtkawcprppravqyshthttnyklssevhndvairprtnlttv
- Chain '2':
Sequence; same for both SEQRES and ATOM records: (download)
>1c8m2 (2:)
sdriiqitrgdstitsqdvanavvgygvwphyltpqdataidkptqpdtssnrfytldsk
mwnstskgwwwklpdalkdmgifgenmfyhflgrsgytvhvqcnaskfhqgtllvvmipe
hqlatvnkgnvnagykythpgeagrevgtqvenekqpsddnwlnfdgtllgnllifphqf
inlrsnnsatlivpyvnavpmdsmvrhnnwslviipvcqlqsnnisnivpitvsispmca
efsgaraktvvq
- Chain '3':
Sequence; same for both SEQRES and ATOM records: (download)
>1c8m3 (3:)
glpvyvtpgsgqfmttddmqspcalpwyhptkeifipgevknliemcqvdtlipinstqs
nignvsmytvtlspqtklaeeifaikvdiashplattligeiasyfthwtgslrfsfmfc
gtanttlkvllaytppgigkprsrkeamlgthvvwdvglqstvslvvpwisasqyrfttp
dtyssagyitcwyqtnfvvppntpntaemlcfvsgckdfclrmardtdlhkqtgpitq
- Chain '4':
Sequence, based on SEQRES records: (download)
>1c8m4 (4:)
gaqvsrqnvgthstqnmvsngssinyfninyfkdaassgasrldfsqdpskftdpvkdvl
ekgiptlqspsveacgy
Sequence, based on observed residues (ATOM records): (download)
>1c8m4 (4:)
gaqvsrqsinyfninyfkdaassgasrld