PDB entry 1c5v
View 1c5v on RCSB PDB site
Description: structural basis for selectivity of a small molecule, s1-binding, sub-micromolar inhibitor of urokinase type plasminogen activator
Class: hydrolase
Keywords: selective, S1 site inhibitor, structure-based drug design, urokinase,
trypsin, thrombin
Deposited on
1999-12-22, released
2000-12-22
The last revision prior to the SCOP 1.73 freeze date was dated
2001-09-26, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: 0.198
AEROSPACI score: 0.59
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein (trypsin)
Species: BOS TAURUS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d1c5va_ - Heterogens: CA, MG, HOH