PDB entry 1c5q
View 1c5q on RCSB PDB site
Description: structural basis for selectivity of a small molecule, s1-binding, sub-micromolar inhibitor of urokinase type plasminogen activator
Class: hydrolase
Keywords: selective, S1 site inhibitor, structure-based drug design, urokinase, trypsin, thrombin, HYDROLASE
Deposited on
1999-12-22, released
2000-12-22
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.43 Å
R-factor: 0.197
AEROSPACI score: 0.65
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein (trypsin)
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d1c5qa_ - Heterogens: CA, CL, ESI, HOH