PDB entry 1c4v
View 1c4v on RCSB PDB site
Description: selective non electrophilic thrombin inhibitors with cyclohexyl moieties.
Class: hydrolase/hydrolase inhibitor
Keywords: complex (serine protease-inhibitor), hydrolase, hydrolase-hydrolase inhibitor complex
Deposited on
1999-09-25, released
2000-09-27
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-04, with a file datestamp of
2017-09-29.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain '1':
Compound: thrombin:short chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1c4v.1 - Chain '2':
Compound: thrombin:long chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1c4v.1 - Chain '3':
Compound: hirugen
Database cross-references and differences (RAF-indexed):
- Heterogens: NA, IH2, HOH
PDB Chain Sequences:
- Chain '1':
Sequence; same for both SEQRES and ATOM records: (download)
>1c4v1 (1:)
tfgsgeadcglrplfekksledkterellesyidgr
- Chain '2':
Sequence, based on SEQRES records: (download)
>1c4v2 (2:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1c4v2 (2:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketgqpsvlqvvnlpiverpvckdstriritdnmfc
agykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlk
kwiqkvidqfge
- Chain '3':
No sequence available.