PDB entry 1c0t

View 1c0t on RCSB PDB site
Description: crystal structure of hiv-1 reverse transcriptase in complex with bm+21.1326
Class: transferase
Keywords: hiv-1 reverse transcriptase, aids, non-nucleoside inhibitor, drug design, transferase
Deposited on 1999-07-19, released 2000-07-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-11-12, with a file datestamp of 2014-11-07.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.214
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-1 reverse transcriptase (a-chain)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1c0ta1, d1c0ta2
  • Chain 'B':
    Compound: hiv-1 reverse transcriptase (b-chain)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1c0tb_
  • Heterogens: BM1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1c0tA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagirkvl

    Sequence, based on observed residues (ATOM records): (download) 
    >1c0tA (A:)
pietvpvklkpgmdgpkvkqwpltgkisnpyntpvfaklvdfrelnkrtqdfwevqlgip
hpaglkkkksvtvldvgdayfsvpldedfrkytafyqynvlpqgwkgspaifqssmtkil
epfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppfl
wmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtka
lteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfkn
lktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqa
twipewefvntpplvklwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvt
ltdttnqktelqaiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikk
ekvylawvpah

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1c0tB (B:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records): (download) 
    >1c0tB (B:)
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfhpaglkkkksvtvldvgdayfsvpldedfrkytaftip
sinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgelh
pdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkaltevipl
teeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkya
rmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewe
fvntpplvklwyq