PDB entry 1bwc

View 1bwc on RCSB PDB site
Description: STRUCTURE OF HUMAN GLUTATHIONE REDUCTASE COMPLEXED with AJOENE INHIBITOR AND SUBVERSIVE SUBSTRATE
Class: oxidoreductase
Keywords: oxidoreductase, flavoenzyme, redox-active center
Deposited on 1998-09-23, released 1999-07-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.18
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (glutathione reductase)
    Species: Homo sapiens [TaxId:9606]
    Gene: GOR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1bwca1, d1bwca2, d1bwca3
  • Heterogens: CL, FAD, AJ3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1bwcA (A:)
    acrqepqpqgpppaagavasydylvigggsgglasarraaelgaraavveshklggtcvn
    vgcvpkkvmwntavhsefmhdhadygfpscegkfnwrvikekrdayvsrlnaiyqnnltk
    shieiirghaaftsdpkptievsgkkytaphiliatggmpstphesqipgaslgitsdgf
    fqleelpgrsvivgagyiavemagilsalgsktslmirhdkvlrsfdsmistncteelen
    agvevlkfsqvkevkktlsglevsmvtavpgrlpvmtmipdvdcllwaigrvpntkdlsl
    nklgiqtddkghiivdefqntnvkgiyavgdvcgkalltpvaiaagrklahrlfeykeds
    kldynniptvvfshppigtvgltedeaihkygienvktystsftpmyhavtkrktkcvmk
    mvcankeekvvgihmqglgcdemlqgfavavkmgatkadfdntvaihptsseelvtlr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bwcA (A:)
    vasydylvigggsgglasarraaelgaraavveshklggtcvnvgcvpkkvmwntavhse
    fmhdhadygfpscegkfnwrvikekrdayvsrlnaiyqnnltkshieiirghaaftsdpk
    ptievsgkkytaphiliatggmpstphesqipgaslgitsdgffqleelpgrsvivgagy
    iavemagilsalgsktslmirhdkvlrsfdsmistncteelenagvevlkfsqvkevkkt
    lsglevsmvtavpgrlpvmtmipdvdcllwaigrvpntkdlslnklgiqtddkghiivde
    fqntnvkgiyavgdvcgkalltpvaiaagrklahrlfeykedskldynniptvvfshppi
    gtvgltedeaihkygienvktystsftpmyhavtkrktkcvmkmvcankeekvvgihmqg
    lgcdemlqgfavavkmgatkadfdntvaihptsseelvtlr