PDB entry 1bth
View 1bth on RCSB PDB site
Description: structure of thrombin complexed with bovine pancreatic trypsin inhibitor
Class: complex (serine protease/inhibitor)
Keywords: thrombin inhibitor, serine proteinase kunitz-like inhibitor, (serine protease/inhibitor), complex (serine protease/inhibitor) complex
Deposited on
1996-12-03, released
1997-12-24
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.196
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: thrombin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P00734 (0-End)
- conflict (148)
- engineered (201)
Domains in SCOPe 2.06: d1bth.1 - Chain 'J':
Compound: thrombin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1bth.2 - Chain 'K':
Compound: thrombin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P00734 (0-End)
- conflict (148)
- engineered (201)
Domains in SCOPe 2.06: d1bth.2 - Chain 'L':
Compound: thrombin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1bth.1 - Chain 'P':
Compound: bovine pancreatic trypsin inhibitor
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1bthp_ - Chain 'Q':
Compound: bovine pancreatic trypsin inhibitor
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1bthq_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'H':
Sequence, based on SEQRES records: (download)
>1bthH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwttnvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacqgdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1bthH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwttnvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacqgdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvi
- Chain 'J':
Sequence, based on SEQRES records: (download)
>1bthJ (J:)
tfgsgeadcglrplfekksledkterellesyidgr
Sequence, based on observed residues (ATOM records): (download)
>1bthJ (J:)
geadcglrplfekksledkterellesyidg
- Chain 'K':
Sequence, based on SEQRES records: (download)
>1bthK (K:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwttnvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacqgdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1bthK (K:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwttnvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacqgdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvi
- Chain 'L':
Sequence, based on SEQRES records: (download)
>1bthL (L:)
tfgsgeadcglrplfekksledkterellesyidgr
Sequence, based on observed residues (ATOM records): (download)
>1bthL (L:)
geadcglrplfekksledkterellesyidg
- Chain 'P':
Sequence; same for both SEQRES and ATOM records: (download)
>1bthP (P:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga
- Chain 'Q':
Sequence; same for both SEQRES and ATOM records: (download)
>1bthQ (Q:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga