PDB entry 1bm2

View 1bm2 on RCSB PDB site
Description: grb2-sh2 domain in complex with cyclo-[n-alpha-acetyl-l-thi alysyl-o-phosphotyrosyl-valyl-asparagyl-valyl-prolyl] (pkf273-791)
Class: hormone/growth factor
Keywords: sh2 domain, signal transduction, adaptor protein, ras pathway, cyclic peptide
Deposited on 1998-07-27, released 1998-08-05
The last revision prior to the SCOP 1.73 freeze date was dated 1999-12-29, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.197
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (growth factor receptor bound protein 2)
    Species: HOMO SAPIENS
    Gene: GRB2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1bm2a_
  • Chain 'L':
    Compound: protein (pkf273-791)
  • Heterogens: ACE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1bm2A (A:)
gspknyiemkphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvq
hfkvlrdgagkyflwvvkfnslnelvdyhrstsvsrnqqiflrdieqvpqqptyvqa

    Sequence, based on observed residues (ATOM records): (download) 
    >1bm2A (A:)
mkphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdg
agkyflwvvkfnslnelvdyhrstsvsrnqqiflrdie

  • Chain 'L':
    No sequence available.