PDB entry 1bj1

View 1bj1 on RCSB PDB site
Description: vascular endothelial growth factor in complex with a neutralizing antibody
Class: complex (antibody/antigen)
Keywords: complex (antibody/antigen), angiogenic factor
Deposited on 1998-06-30, released 1999-01-13
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.196
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1BJ1 (0-End)
    Domains in SCOPe 2.03: d1bj1h1, d1bj1h2
  • Chain 'J':
    Compound: fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • GB AAA87674 (2-End)
      • conflict (9)
      • conflict (23)
      • conflict (27)
      • conflict (30-31)
      • conflict (33)
      • conflict (45)
      • conflict (49-50)
      • conflict (54)
      • conflict (69)
      • conflict (75)
      • conflict (80)
      • conflict (86)
      • conflict (89)
      • insertion (91)
      • conflict (92-93)
    Domains in SCOPe 2.03: d1bj1j1, d1bj1j2
  • Chain 'K':
    Compound: fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1BJ1 (0-End)
    Domains in SCOPe 2.03: d1bj1k1, d1bj1k2
  • Chain 'L':
    Compound: fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • GB AAA87674 (2-End)
      • conflict (9)
      • conflict (23)
      • conflict (27)
      • conflict (30-31)
      • conflict (33)
      • conflict (45)
      • conflict (49-50)
      • conflict (54)
      • conflict (69)
      • conflict (75)
      • conflict (80)
      • conflict (86)
      • conflict (89)
      • insertion (91)
      • conflict (92-93)
    Domains in SCOPe 2.03: d1bj1l1, d1bj1l2
  • Chain 'V':
    Compound: vascular endothelial growth factor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1bj1v_
  • Chain 'W':
    Compound: vascular endothelial growth factor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1bj1w_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1bj1H (H:)
    evqlvesggglvqpggslrlscaasgytftnygmnwvrqapgkglewvgwintytgepty
    aadfkrrftfsldtskstaylqmnslraedtavyycakyphyygsshwyfdvwgqgtlvt
    vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
    qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdktht
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bj1H (H:)
    evqlvesggglvqpggslrlscaasgytftnygmnwvrqapgkglewvgwintytgepty
    aadfkrrftfsldtskstaylqmnslraedtavyycakyphyygsshwyfdvwgqgtlvt
    vssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
    slssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
    

  • Chain 'J':
    Sequence, based on SEQRES records: (download)
    >1bj1J (J:)
    diqmtqspsslsasvgdrvtitcsasqdisnylnwyqqkpgkapkvliyftsslhsgvps
    rfsgsgsgtdftltisslqpedfatyycqqystvpwtfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrgec
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bj1J (J:)
    diqmtqspsslsasvgdrvtitcsasqdisnylnwyqqkpgkapkvliyftsslhsgvps
    rfsgsgsgtdftltisslqpedfatyycqqystvpwtfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrge
    

  • Chain 'K':
    Sequence, based on SEQRES records: (download)
    >1bj1K (K:)
    evqlvesggglvqpggslrlscaasgytftnygmnwvrqapgkglewvgwintytgepty
    aadfkrrftfsldtskstaylqmnslraedtavyycakyphyygsshwyfdvwgqgtlvt
    vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
    qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdktht
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bj1K (K:)
    evqlvesggglvqpggslrlscaasgytftnygmnwvrqapgkglewvgwintytgepty
    aadfkrrftfsldtskstaylqmnslraedtavyycakyphyygsshwyfdvwgqgtlvt
    vssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
    slssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >1bj1L (L:)
    diqmtqspsslsasvgdrvtitcsasqdisnylnwyqqkpgkapkvliyftsslhsgvps
    rfsgsgsgtdftltisslqpedfatyycqqystvpwtfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrgec
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bj1L (L:)
    diqmtqspsslsasvgdrvtitcsasqdisnylnwyqqkpgkapkvliyftsslhsgvps
    rfsgsgsgtdftltisslqpedfatyycqqystvpwtfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrge
    

  • Chain 'V':
    Sequence, based on SEQRES records: (download)
    >1bj1V (V:)
    gqnhhevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndegle
    cvpteesnitmqimrikphqgqhigemsflqhnkcecrpkkd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bj1V (V:)
    vvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvptee
    snitmqimrikphqgqhigemsflqhnkcecrpk
    

  • Chain 'W':
    Sequence, based on SEQRES records: (download)
    >1bj1W (W:)
    gqnhhevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndegle
    cvpteesnitmqimrikphqgqhigemsflqhnkcecrpkkd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bj1W (W:)
    vvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvptee
    snitmqimrikphqgqhigemsflqhnkcecrpk