PDB entry 1bis

View 1bis on RCSB PDB site
Description: hiv-1 integrase core domain
Class: DNA integration
Keywords: DNA integration, integrase, hiv, hydrolase, aspartyl protease, endonuclease
Deposited on 1998-06-19, released 1998-08-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.204
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-1 integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497 (Start-162)
      • engineered (84)
      • engineered (138)
    Domains in SCOPe 2.07: d1bisa_
  • Chain 'B':
    Compound: hiv-1 integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497 (Start-162)
      • engineered (84)
      • engineered (138)
    Domains in SCOPe 2.07: d1bisb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1bisA (A:)
gshmhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklag
rwpvktvhtdngsnftsttvkaacewagikqefgipynpqsqgviesmnkelkkiigqvr
dqaehlktavqmavfihnkkrkggiggysagerivdiiatdiqdiq

    Sequence, based on observed residues (ATOM records): (download) 
    >1bisA (A:)
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacewagikqefgipiesmnkelkkiigqvrdqaehlktavqmavfih
nkkrkggiggysagerivdiiatdiq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1bisB (B:)
gshmhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklag
rwpvktvhtdngsnftsttvkaacewagikqefgipynpqsqgviesmnkelkkiigqvr
dqaehlktavqmavfihnkkrkggiggysagerivdiiatdiqdiq

    Sequence, based on observed residues (ATOM records): (download) 
    >1bisB (B:)
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacewagikqefgipynpqsqgviesmnkelkkiigqvrdqaehlkta
vqmavfihnkkrkggiggysagerivdiiatdiq