PDB entry 1bgx

View 1bgx on RCSB PDB site
Description: taq polymerase in complex with tp7, an inhibitory fab
Class: complex (polymerase/inhibitor)
Keywords: DNA polymerase, fab, pcr, inhibition, helix-coil dynamics, inhibitor design, complex (polymerase/inhibitor)
Deposited on 1998-06-02, released 1998-10-14
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.189
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: tp7 mab
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • GB AAB06744 (Start-212)
      • conflict (14)
      • conflict (20)
      • conflict (28)
      • conflict (30)
      • conflict (48)
      • conflict (52)
      • conflict (56)
      • conflict (58)
      • insertion (98-101)
      • conflict (102)
      • insertion (104)
      • conflict (106-107)
      • conflict (113-114)
      • conflict (118)
      • conflict (123)
      • conflict (132)
      • conflict (151)
      • conflict (183)
      • conflict (190-192)
      • conflict (210)
    Domains in SCOPe 2.03: d1bgxh1, d1bgxh2
  • Chain 'L':
    Compound: tp7 mab
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • GB AAC28911 (4-209)
      • conflict (16)
      • conflict (20)
      • conflict (30-32)
      • conflict (38)
      • conflict (40)
      • conflict (43)
      • conflict (45)
      • conflict (49-51)
      • conflict (54)
      • conflict (58)
      • conflict (75)
      • conflict (83)
      • conflict (85)
      • conflict (87)
      • conflict (91)
    Domains in SCOPe 2.03: d1bgxl1, d1bgxl2
  • Chain 'T':
    Compound: taq DNA polymerase
    Species: Thermus aquaticus [TaxId:271]
    Gene: TAQ
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1bgxt1, d1bgxt2, d1bgxt3, d1bgxt4
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1bgxH (H:)
    evqlqesgpglvkpyqslslsctvtgysitsdyawnwirqfpgnklewmgyitysgttdy
    npslksrisitrdtsknqfflqlnsvttedtatyycaryyygywyfdvwgqgttltvssa
    kttapsvyplapvssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsdlytlsss
    vtvtsstwpsqsitcnvahpasstkvdkkiepr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bgxH (H:)
    qesgpglvkpyqslslsctvtgysitsdyawnwirqfpgnklewmgyitysgttdynpsl
    ksrisitrdtsknqfflqlnsvttedtatyycaryyygywyfdvwgqgttltvssaktta
    psvyplapvssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsdlytlsssvtvt
    sstwpsqsitcnvahpasstkvdkkiepr
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1bgxL (L:)
    diqmtqspaimsaspgekvtmtcsasssvsymywyqqkpgssprlliydstnlasgvpvr
    fsgsgsgtsysltisrmeaedaatyycqqwstypltfgagtklelkradaaptvsifpps
    seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
    tkdeyerhnsytceathktstspivksfnr
    

  • Chain 'T':
    Sequence, based on SEQRES records: (download)
    >1bgxT (T:)
    mrgmlplfepkgrvllvdghhlayrtfhalkglttsrgepvqavygfaksllkalkedgd
    avivvfdakapsfrheayggykagraptpedfprqlalikelvdllglarlevpgyeadd
    vlaslakkaekegyevriltadkdlyqllsdrihvlhpegylitpawlwekyglrpdqwa
    dyraltgdesdnlpgvkgigektarklleewgsleallknldrlkpairekilahmddlk
    lswdlakvrtdlplevdfakrrepdrerlraflerlefgsllhefgllespkaleeapwp
    ppegafvgfvlsrkepmwadllalaaarggrvhrapepykalrdlkeargllakdlsvla
    lreglglppgddpmllaylldpsnttpegvarryggewteeageraalserlfanlwgrl
    egeerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlagh
    pfnlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltk
    lkstyidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafia
    eegwllvaldysqielrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrr
    aaktinfgvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyv
    etlfgrrryvpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarml
    lqvhdelvleapkeraeavarlakevmegvyplavplevevgigedwlsake
    

    Sequence, based on observed residues (ATOM records): (download)
    >1bgxT (T:)
    mrgmlplfepkgrvllvdghhlayrtfhalkglttsrgepvqavygfaksllkalkedgd
    avivvfdakapsfrheayggykagraptpedfprqlalikelvdllglarlevpgyeadd
    vlaslakkaekegyevriltadkdlyqllsdrihvlhpegylitpawlwekyglrpdqwa
    dyraltgdesdnlpgvkgigektarklleewgsleallknldrlkpairekilahmddlk
    lswdlakvrtdlplevdfakrrepdrerlraflerlefgsllhefgllespkaleeapwp
    ppegafvgfvlsrkepmwadllalaaarggrvhrapepykalrdlkeargllakdlsvla
    lreglglppgddpmllaylldpsnttpegvarryggewteeageraalserlfanlwgrl
    egeerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlagh
    pfnlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltk
    lkstyidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafia
    eegwllvaldysqielrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrr
    aaktinfgvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyv
    etlfgrrryvpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarml
    lqvhdelvleaaeavarlakevmegvyplavplevevgigedwlsake