PDB entry 1b65

View 1b65 on RCSB PDB site
Description: Structure of l-aminopeptidase d-ala-esterase/amidase from ochrobactrum anthropi, a prototype for the serine aminopeptidases, reveals a new variant among the ntn hydrolase fold
Class: hydrolase
Keywords: hydrolase, peptide degradation, ntn hydrolase
Deposited on 1999-01-20, released 1999-07-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: 0.17
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (aminopeptidase)
    Species: Ochrobactrum anthropi [TaxId:529]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1b65a_
  • Chain 'B':
    Compound: protein (aminopeptidase)
    Species: Ochrobactrum anthropi [TaxId:529]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1b65b_
  • Chain 'C':
    Compound: protein (aminopeptidase)
    Species: Ochrobactrum anthropi [TaxId:529]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1b65c_
  • Chain 'D':
    Compound: protein (aminopeptidase)
    Species: Ochrobactrum anthropi [TaxId:529]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1b65d_
  • Chain 'E':
    Compound: protein (aminopeptidase)
    Species: Ochrobactrum anthropi [TaxId:529]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1b65e_
  • Chain 'F':
    Compound: protein (aminopeptidase)
    Species: Ochrobactrum anthropi [TaxId:529]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1b65f_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1b65A (A:)
mtsqtptrkprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvt
ailphmqsetpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvr
wmvdryastyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegnc
gggtgmitygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgt
pqsqlqergsiivvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanq
rpmqhrsapfldvemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaid
herlravlrqygrla

    Sequence, based on observed residues (ATOM records): (download) 
    >1b65A (A:)
kprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvtailphmqs
etpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvrwmvdryas
tyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegncgggtgmit
ygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgtpqsqlsii
vvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanqrpmqhrsapfld
vemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaidherlravlrqyg
rla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1b65B (B:)
mtsqtptrkprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvt
ailphmqsetpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvr
wmvdryastyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegnc
gggtgmitygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgt
pqsqlqergsiivvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanq
rpmqhrsapfldvemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaid
herlravlrqygrla

    Sequence, based on observed residues (ATOM records): (download) 
    >1b65B (B:)
kprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvtailphmqs
etpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvrwmvdryas
tyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegncgggtgmit
ygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgtpqsqlsii
vvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanqrpmqhrsapfld
vemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaidherlravlrqyg
rla

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1b65C (C:)
mtsqtptrkprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvt
ailphmqsetpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvr
wmvdryastyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegnc
gggtgmitygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgt
pqsqlqergsiivvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanq
rpmqhrsapfldvemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaid
herlravlrqygrla

    Sequence, based on observed residues (ATOM records): (download) 
    >1b65C (C:)
kprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvtailphmqs
etpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvrwmvdryas
tyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegncgggtgmit
ygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgtpqsqlsii
vvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanqrpmqhrsapfld
vemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaidherlravlrqyg
rla

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1b65D (D:)
mtsqtptrkprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvt
ailphmqsetpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvr
wmvdryastyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegnc
gggtgmitygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgt
pqsqlqergsiivvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanq
rpmqhrsapfldvemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaid
herlravlrqygrla

    Sequence, based on observed residues (ATOM records): (download) 
    >1b65D (D:)
kprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvtailphmqs
etpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvrwmvdryas
tyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegncgggtgmit
ygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgtpqsqlsii
vvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanqrpmqhrsapfld
vemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaidherlravlrqyg
rla

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1b65E (E:)
mtsqtptrkprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvt
ailphmqsetpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvr
wmvdryastyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegnc
gggtgmitygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgt
pqsqlqergsiivvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanq
rpmqhrsapfldvemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaid
herlravlrqygrla

    Sequence, based on observed residues (ATOM records): (download) 
    >1b65E (E:)
kprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvtailphmqs
etpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvrwmvdryas
tyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegncgggtgmit
ygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgtpqsqlsii
vvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanqrpmqhrsapfld
vemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaidherlravlrqyg
rla

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1b65F (F:)
mtsqtptrkprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvt
ailphmqsetpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvr
wmvdryastyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegnc
gggtgmitygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgt
pqsqlqergsiivvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanq
rpmqhrsapfldvemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaid
herlravlrqygrla

    Sequence, based on observed residues (ATOM records): (download) 
    >1b65F (F:)
kprardlglpftgvtgpynaitdvdgvgvgfqtiieneprpgrkrparsgvtailphmqs
etpvpvyagvhrfngngemtgthwiedggyflgpvvitnthgigmahhatvrwmvdryas
tyqtddflwimpvvaetydgalndingfpvteadvrkaldnvasgpvqegncgggtgmit
ygfkggtgtasrvvefggrsftigalvqanhgqrdwltiagvpvgqhmrdgtpqsqlsii
vvlatdlplmphqlkrlarrasigigrngtpggnnsgdifiafstanqrpmqhrsapfld
vemvndepldtvylaavdsveeavvnamiaaedmggtpfdrllvqaidherlravlrqyg
rla