PDB entry 1b5g

View 1b5g on RCSB PDB site
Description: human thrombin complexed with novel synthetic peptide mimetic inhibitor and hirugen
Class: complex (serine protease/inhibitor)
Keywords: complex (serine protease/inhibitor)
Deposited on 1998-03-05, released 1998-05-27
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-07-06.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: 0.164
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: alpha-thrombin
    Species: HOMO SAPIENS
    Domains in SCOP 1.73: d1b5g.1
  • Chain 'I':
    Compound: hirugen
    Species: Hirudo medicinalis
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09945 (Start-11)
      • modified residue (10)
  • Chain 'L':
    Compound: alpha-thrombin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1b5g.1
  • Chain 'R':
    Compound: mol168
  • Heterogens: NA, THZ, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1b5gH (H:)
    ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
    vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
    pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
    itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
    thvfrlkkwiqkvidqfge
    

    Sequence, based on observed residues (ATOM records): (download)
    >1b5gH (H:)
    ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
    vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
    pdretaasllqagykgrvtgwgnlkegqpsvlqvvnlpiverpvckdstriritdnmfca
    gykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkk
    wiqkvidqfg
    

  • Chain 'I':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >1b5gL (L:)
    tfgsgeadcglrplfekksledkterellesyidgr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1b5gL (L:)
    eadcglrplfekksledkterellesyid
    

  • Chain 'R':
    No sequence available.