PDB entry 1b4j
View 1b4j on RCSB PDB site
Description: comparison of the three-dimensional structures of a humanized and a chimeric fab of an anti-gamma-interferon antibody
Class: antibody engineering
Keywords: antibody engineering, humanized and chimeric antibodies, fab, x-ray structures, gamma-interferon
Deposited on
1998-12-22, released
1999-06-15
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.193
AEROSPACI score: -1.78
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1b4jh1, d1b4jh2 - Chain 'L':
Compound: antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- EMBL CAA65061 (2-213)
- conflict (8)
- conflict (10-14)
- conflict (16)
- conflict (20-21)
- conflict (23)
- conflict (26-30)
- conflict (32-33)
- conflict (40-42)
- conflict (49)
- conflict (52-55)
- conflict (59)
- conflict (62)
- conflict (67)
- conflict (77)
- conflict (79)
- conflict (82)
- conflict (84)
- conflict (86)
- conflict (88)
- conflict (91-93)
- conflict (95)
- conflict (99)
- conflict (102)
Domains in SCOPe 2.04: d1b4jl1, d1b4jl2
PDB Chain Sequences:
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>1b4jH (H:)
evqlqqpgadlvmpgapvklsclasgyiftsswinwvkqrpgrglewigridpsdgevhy
nqdfkdkatltvdkssstayiqlnsltsedsavyycargflpwfadwgqgtlvtvsaast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>1b4jL (L:)
nivmtqspksmyvsigervtlsckasenvdtyvswyqqkpeqspklliygasnrytgvpd
rftgsgsatdftltissvqaedladyhcgqsynypftfgsgtkleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec