PDB entry 1b41

View 1b41 on RCSB PDB site
Description: human acetylcholinesterase complexed with fasciculin-II, glycosylated protein
Class: hydrolase/toxin
Keywords: serine esterase, human-acetylcholinesterase, hydrolase, snake toxin, hydrolase-toxin complex
Deposited on 1999-01-05, released 2001-01-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-02, with a file datestamp of 2021-05-28.
Experiment type: XRAY
Resolution: 2.76 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACHE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1b41a_
  • Chain 'B':
    Compound: fasciculin-2
    Species: Dendroaspis angusticeps [TaxId:8618]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01403 (0-60)
      • engineered (46)
    Domains in SCOPe 2.08: d1b41b_
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1b41A (A:)
daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
rrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvd
gdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvr
vgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgar
vyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfa
rtgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat

    Sequence, based on observed residues (ATOM records): (download) 
    >1b41A (A:)
daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
rrratqlahlvgcpndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdgdflsd
tpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrvgvpqv
sdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvyayvf
ehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfartgdpn
eppkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1b41B (B:)
tmcyshtttsrailtncgenscyrksrrhppkmvlgrgcgcppgddnlevkcctspdkcn
y