PDB entry 1ay0

View 1ay0 on RCSB PDB site
Description: identification of catalytically important residues in yeast transketolase
Class: transferase
Keywords: transketolase mechanism, thiamin diphosphate, mutant, transferase, ketone residues
Deposited on 1997-11-13, released 1998-05-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.193
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: transketolase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: TKL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23254 (Start-679)
      • engineered (262)
    Domains in SCOPe 2.07: d1ay0a1, d1ay0a2, d1ay0a3
  • Chain 'B':
    Compound: transketolase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: TKL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23254 (Start-679)
      • engineered (262)
    Domains in SCOPe 2.07: d1ay0b1, d1ay0b2, d1ay0b3
  • Heterogens: CA, TPP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ay0A (A:)
mtqftdidklavstirilavdtvskansghpgaplgmapaahvlwsqmrmnptnpdwinr
drfvlsnghavallysmlhltgydlsiedlkqfrqlgsrtpghpefelpgvevttgplgq
gisnavgmamaqanlaatynkpgftlsdnytyvflgdgclqegisseasslaghlklgnl
iaiyddnkitidgatsisfdedvakryeaygwevlyvengnedlagiakaiaqaklskdk
ptlikmtttigygslhagshsvagaplkaddvkqlkskfgfnpdksfvvpqevydhyqkt
ilkpgveannkwnklfseyqkkfpelgaelarrlsgqlpanwesklptytakdsavatrk
lsetvledvynqlpeliggsadltpsnltrwkealdfqppssgsgnysgryirygireha
mgaimngisafganykpyggtflnfvsyaagavrlsalsghpviwvathdsigvgedgpt
hqpietlahfrslpniqvwrpadgnevsaayknsleskhtpsiialsrqnlpqlegssie
saskggyvlqdvanpdiilvatgsevslsveaaktlaaknikarvvslpdfftfdkqple
yrlsvlpdnvpimsvevlattcwgkyahqsfgidrfgasgkapevfkffgftpegvaera
qktiafykgdklisplkkaf

    Sequence, based on observed residues (ATOM records): (download) 
    >1ay0A (A:)
qftdidklavstirilavdtvskansghpgaplgmapaahvlwsqmrmnptnpdwinrdr
fvlsnghavallysmlhltgydlsiedlkqfrqlgsrtpghpefelpgvevttgplgqgi
snavgmamaqanlaatynkpgftlsdnytyvflgdgclqegisseasslaghlklgnlia
iyddnkitidgatsisfdedvakryeaygwevlyvengnedlagiakaiaqaklskdkpt
likmtttigygslhagshsvagaplkaddvkqlkskfgfnpdksfvvpqevydhyqktil
kpgveannkwnklfseyqkkfpelgaelarrlsgqlpanwesklptytakdsavatrkls
etvledvynqlpeliggsadltpsnltrwkealdfqppssgsgnysgryirygirehamg
aimngisafganykpyggtflnfvsyaagavrlsalsghpviwvathdsigvgedgpthq
pietlahfrslpniqvwrpadgnevsaayknsleskhtpsiialsrqnlpqlegssiesa
skggyvlqdvanpdiilvatgsevslsveaaktlaaknikarvvslpdfftfdkqpleyr
lsvlpdnvpimsvevlattcwgkyahqsfgidrfgasgkapevfkffgftpegvaeraqk
tiafykgdklisplkkaf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ay0B (B:)
mtqftdidklavstirilavdtvskansghpgaplgmapaahvlwsqmrmnptnpdwinr
drfvlsnghavallysmlhltgydlsiedlkqfrqlgsrtpghpefelpgvevttgplgq
gisnavgmamaqanlaatynkpgftlsdnytyvflgdgclqegisseasslaghlklgnl
iaiyddnkitidgatsisfdedvakryeaygwevlyvengnedlagiakaiaqaklskdk
ptlikmtttigygslhagshsvagaplkaddvkqlkskfgfnpdksfvvpqevydhyqkt
ilkpgveannkwnklfseyqkkfpelgaelarrlsgqlpanwesklptytakdsavatrk
lsetvledvynqlpeliggsadltpsnltrwkealdfqppssgsgnysgryirygireha
mgaimngisafganykpyggtflnfvsyaagavrlsalsghpviwvathdsigvgedgpt
hqpietlahfrslpniqvwrpadgnevsaayknsleskhtpsiialsrqnlpqlegssie
saskggyvlqdvanpdiilvatgsevslsveaaktlaaknikarvvslpdfftfdkqple
yrlsvlpdnvpimsvevlattcwgkyahqsfgidrfgasgkapevfkffgftpegvaera
qktiafykgdklisplkkaf

    Sequence, based on observed residues (ATOM records): (download) 
    >1ay0B (B:)
qftdidklavstirilavdtvskansghpgaplgmapaahvlwsqmrmnptnpdwinrdr
fvlsnghavallysmlhltgydlsiedlkqfrqlgsrtpghpefelpgvevttgplgqgi
snavgmamaqanlaatynkpgftlsdnytyvflgdgclqegisseasslaghlklgnlia
iyddnkitidgatsisfdedvakryeaygwevlyvengnedlagiakaiaqaklskdkpt
likmtttigygslhagshsvagaplkaddvkqlkskfgfnpdksfvvpqevydhyqktil
kpgveannkwnklfseyqkkfpelgaelarrlsgqlpanwesklptytakdsavatrkls
etvledvynqlpeliggsadltpsnltrwkealdfqppssgsgnysgryirygirehamg
aimngisafganykpyggtflnfvsyaagavrlsalsghpviwvathdsigvgedgpthq
pietlahfrslpniqvwrpadgnevsaayknsleskhtpsiialsrqnlpqlegssiesa
skggyvlqdvanpdiilvatgsevslsveaaktlaaknikarvvslpdfftfdkqpleyr
lsvlpdnvpimsvevlattcwgkyahqsfgidrfgasgkapevfkffgftpegvaeraqk
tiafykgdklisplkkaf