PDB entry 1awh

View 1awh on RCSB PDB site
Description: novel covalent thrombin inhibitor from plant extract
Class: complex (protease/inhibitor)
Keywords: PROTEINASE, BLOOD COAGULATION, TRYPSIN LIKE PROTEINASE, COMPLEX (PROTEASE-INHIBITOR), COMPLEX (PROTEASE-INHIBITOR) complex
Deposited on 1997-10-02, released 1998-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-04-18, with a file datestamp of 2018-04-13.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1awh.1
  • Chain 'B':
    Compound: alpha thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1awh.1
  • Chain 'C':
    Compound: alpha thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1awh.2
  • Chain 'D':
    Compound: alpha thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1awh.2
  • Heterogens: GR3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1awhA (A:)
tfgsgeadcglrplfekksledkterellesyidgr

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1awhB (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1awhC (C:)
tfgsgeadcglrplfekksledkterellesyidgr

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1awhD (D:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge