PDB entry 1awh

View 1awh on RCSB PDB site
Description: novel covalent thrombin inhibitor from plant extract
Class: complex (protease/inhibitor)
Keywords: proteinase, blood coagulation, trypsin like proteinase, complex (protease/inhibitor)
Deposited on 1997-10-02, released 1998-10-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.202
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1awh.1
  • Chain 'B':
    Compound: alpha thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1awh.1
  • Chain 'C':
    Compound: alpha thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1awh.2
  • Chain 'D':
    Compound: alpha thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1awh.2
  • Heterogens: GR3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1awhA (A:)
    tfgsgeadcglrplfekksledkterellesyidgr
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1awhB (B:)
    ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
    vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
    pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
    itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
    thvfrlkkwiqkvidqfge
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1awhC (C:)
    tfgsgeadcglrplfekksledkterellesyidgr
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1awhD (D:)
    ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
    vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
    pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
    itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
    thvfrlkkwiqkvidqfge