PDB entry 1aui

View 1aui on RCSB PDB site
Description: human calcineurin heterodimer
Class: hydrolase
Keywords: hydrolase, phosphatase, immunosuppression
Deposited on 1997-08-27, released 1997-12-03
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.187
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine phosphatase 2b
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1auia_
  • Chain 'B':
    Compound: serine/threonine phosphatase 2b
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1auib_
  • Heterogens: CA, ZN, FE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1auiA (A:)
msepkaidpklsttdrvvkavpfppshrltakevfdndgkprvdilkahlmkegrleesv
alriitegasilrqeknlldidapvtvcgdihgqffdlmklfevggspantrylflgdyv
drgyfsiecvlylwalkilypktlfllrgnhecrhlteyftfkqeckikyservydacmd
afdclplaalmnqqflcvhgglspeintlddirkldrfkeppaygpmcdilwsdpledfg
nektqehfthntvrgcsyfysypavceflqhnnllsilraheaqdagyrmyrksqttgfp
slitifsapnyldvynnkaavlkyennvmnirqfncsphpywlpnfmdvftwslpfvgek
vtemlvnvlnicsddelgseedgfdgataaarkevirnkiraigkmarvfsvlreesesv
ltlkgltptgmlpsgvlsggkqtlqsatveaieadeaikgfspqhkitsfeeakgldrin
ermpprrdampsdanlnsinkaltsetngtdsngsnssniq

    Sequence, based on observed residues (ATOM records): (download) 
    >1auiA (A:)
tdrvvkavpfppshrltakevfdndgkprvdilkahlmkegrleesvalriitegasilr
qeknlldidapvtvcgdihgqffdlmklfevggspantrylflgdyvdrgyfsiecvlyl
walkilypktlfllrgnhecrhlteyftfkqeckikyservydacmdafdclplaalmnq
qflcvhgglspeintlddirkldrfkeppaygpmcdilwsdpledfgnektqehfthntv
rgcsyfysypavceflqhnnllsilraheaqdagyrmyrksqttgfpslitifsapnyld
vynnkaavlkyennvmnirqfncsphpywlpnfmdvftwslpfvgekvtemlvnvlnics
sfeeakgldrinermppr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1auiB (B:)
gneasyplemcshfdadeikrlgkrfkkldldnsgslsveefmslpelqqnplvqrvidi
fdtdgngevdfkefiegvsqfsvkgdkeqklrfafriydmdkdgyisngelfqvlkmmvg
nnlkdtqlqqivdktiinadkdgdgrisfeefcavvggldihkkmvvdv

    Sequence, based on observed residues (ATOM records): (download) 
    >1auiB (B:)
syplemcshfdadeikrlgkrfkkldldnsgslsveefmslpelqqnplvqrvidifdtd
gngevdfkefiegvsqfsvkgdkeqklrfafriydmdkdgyisngelfqvlkmmvgnnlk
dtqlqqivdktiinadkdgdgrisfeefcavvggldihkkmvvdv