PDB entry 1ao7

View 1ao7 on RCSB PDB site
Description: complex between human T-cell receptor, viral peptide (tax), and hla-a 0201
Class: complex (MHC/viral peptide/receptor)
Keywords: class I MHC, T-cell receptor, viral peptide, complex (MHC-viral peptide-receptor, complex (MHC-viral peptide-receptor) complex
Deposited on 1997-07-21, released 1997-09-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-05-25, with a file datestamp of 2016-05-20.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: -1.82 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla-a 0201
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A 0201
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1ao7a1, d1ao7a2
  • Chain 'B':
    Compound: beta-2 microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: V BETA 12.3 [BV13S1] - D BETA 2.1 - J BETA 2.1 -
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • conflict (67)
      • conflict (91)
    Domains in SCOPe 2.07: d1ao7b2, d1ao7b3
  • Chain 'C':
    Compound: tax peptide
    Species: Primate T-lymphotropic virus 1 [TaxId:11908]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: t cell receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: V ALPHA 2.3 [AV2S1A2] - J ALPHA 24 - C ALPHA
    Database cross-references and differences (RAF-indexed):
    • PDB 1AO7 (0-End)
    Domains in SCOPe 2.07: d1ao7d_
  • Chain 'E':
    Compound: t cell receptor beta
    Species: Homo sapiens [TaxId:9606]
    Gene: V BETA 12.3 [BV13S1] - D BETA 2.1 - J BETA 2.1 - C BETA 2
    Database cross-references and differences (RAF-indexed):
    • GB AAC08953 (Start-244)
      • conflict (93-101)
      • conflict (104)
      • conflict (113)
      • conflict (189)
    Domains in SCOPe 2.07: d1ao7e1, d1ao7e2
  • Heterogens: EMC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1ao7A (A:)
    gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
    kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
    rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgqeqrytchvqheglpkpltlrwe
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ao7A (A:)
    gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
    kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
    rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgqeqrytchvqheglpkpltlrw
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1ao7B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllycteftptekdeyacrvnhvtlsqpcivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1ao7D (D:)
    keveqnsgplsvpegaiaslnctysdrgsqsffwyrqysgkspelimsiysngdkedgrf
    taqlnkasqyvsllirdsqpsdsatylcavttdswgklqfgagtqvvvtpdiqnpdpavy
    qlrdskssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnksd
    facanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ao7D (D:)
    keveqnsgplsvpegaiaslnctysdrgsqsffwyrqysgkspelimsiysngdkedgrf
    taqlnkasqyvsllirdsqpsdsatylcavttdswgklqfgagtqvvvtpdiqnp
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1ao7E (E:)
    nagvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqgev
    pngynvsrsttedfplrllsaapsqtsvyfcasrpglaggrpeqyfgpgtrltvtedlkn
    vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqplke
    qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
    wgrad
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ao7E (E:)
    gvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqgevpn
    gynvsrsttedfplrllsaapsqtsvyfcasrpglaggrpeqyfgpgtrltvtedlknvf
    ppevavflvclatgfypdhvelswwvngkevhsgvstdpqplyalssrlrvsatfwqnpr
    nhfrcqvqfyglakpvtqivsaeawgrad