PDB entry 1aj6

View 1aj6 on RCSB PDB site
Description: novobiocin-resistant mutant (r136h) of the n-terminal 24 kda fragment of DNA gyrase b complexed with novobiocin at 2.3 angstroms resolution
Class: topoisomerase
Keywords: topoisomerase, gyrase, novobiocin, antibiotic, resistant mutant
Deposited on 1997-05-15, released 1998-05-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.206
AEROSPACI score: -1.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gyrase
    Species: Escherichia coli [TaxId:562]
    Gene: GYRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06982
      • engineered (134)
    Domains in SCOPe 2.07: d1aj6a_
  • Heterogens: NOV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1aj6A (A:)
snsydsssikvlkgldavrkrpgmyigdtddgtglhhmvfevvdnaidealaghckeiiv
tihadnsvsvqddgrgiptgihpeegvsaaevimtvlhaggkfddnsykvsgglhgvgvs
vvnalsqklelviqhegkihrqiyehgvpqaplavtgetektgtmvrfwpsletftnvte
feyeilakrlrelsflnsgvsirlrdkrdgkedhfhyeg

    Sequence, based on observed residues (ATOM records): (download) 
    >1aj6A (A:)
vlkgldavrkrpgmyigdtddgtglhhmvfevvdnaidealaghckeiivtihadnsvsv
qddgrgiptgivsaaevimtvlhaggkfsgglhgvgvsvvnalsqklelviqhegkihrq
iyehgvpqaplavtgetektgtmvrfwpsletftnvtefeyeilakrlrelsflnsgvsi
rlrdkrdgkedhfh