PDB entry 1adq

View 1adq on RCSB PDB site
Description: crystal structure of a human igm rheumatoid factor fab in complex with its autoantigen igg fc
Class: complex (immunoglobulin/autoantigen)
Keywords: complex (immunoglobulin/autoantigen), rheumatoid factor auto-antibody complex
Deposited on 1997-02-18, released 1998-09-16
The last revision prior to the SCOP 1.73 freeze date was dated 1998-09-16, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 3.15 Å
R-factor: 0.225
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: igg4 rea fc
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01861 (0-205)
      • conflict (34)
      • conflict (45)
      • conflict (56)
      • conflict (74)
      • conflict (77)
    Domains in SCOP 1.73: d1adqa1, d1adqa2
  • Chain 'H':
    Compound: igm-lambda rf-an fab (heavy chain)
    Species: HOMO SAPIENS
    Domains in SCOP 1.73: d1adqh1, d1adqh2
  • Chain 'L':
    Compound: igm-lambda rf-an fab (light chain)
    Species: HOMO SAPIENS
    Domains in SCOP 1.73: d1adql1, d1adql2

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1adqA (A:)
psvflfppkpkdtlmisrtpevtcvvvdvsqedpqvqfnwyvdgvqvhnaktkpreqqfn
styrvvsvltvlhqnwldgkeykckvsnkglpssiektiskakgqprepqvytlppsqee
mtknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflysrltvdksrw
qegnvfscsvmhealhnhytqkslsl

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1adqH (H:)
evqlvesggglvqpgrslrlscvtsgftfddyamhwvrqspgkglewvsgiswntgtiiy
adsvkgrfiisrdnaknslylqmnslrvedtalyycaktrsyvvaaeyyfhywgqgilvt
vssgsasaptlfplvscensnpsstvavgclaqdflpdsitfswkyknnsdisstrgfps
vlrggkyaatsqvllpskdvmqgtnehvvckvqhpngnkekdvpl

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1adqL (L:)
yvltqppsvsvapgqtaritcggnnigsksvhwyqqkpgqapvlvvyddsdrppgiperf
sgsnsgntatltisrveagdeadyycqvwdsssdhavfgggtkltvlgqpkaapsvtlfp
psseelqankatlvclisdfypgavtvawkadgspvkagvetttpskqsnnkyaassyls
ltpeqwkshksyscqvthegstvektvaptecs