PDB entry 1a94

View 1a94 on RCSB PDB site
Description: structural basis for specificity of retroviral proteases
Class: hydrolase/hydrolase inhibitor
Keywords: human immunodeficiency virus protease, rous sarcoma virus protease, protein-mediated interaction, viral maturation, hydrolase-hydrolase inhibitor complex
Deposited on 1998-04-16, released 1999-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.182
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protease
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03367 (0-98)
      • engineered (6)
      • engineered (32)
      • engineered (42)
      • engineered (62)
      • engineered (66)
      • engineered (94)
    Domains in SCOPe 2.08: d1a94a_
  • Chain 'B':
    Compound: Protease
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03367 (0-98)
      • engineered (6)
      • engineered (32)
      • engineered (42)
      • engineered (62)
      • engineered (66)
      • engineered (94)
    Domains in SCOPe 2.08: d1a94b_
  • Chain 'D':
    Compound: Protease
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03367 (0-98)
      • engineered (6)
      • engineered (32)
      • engineered (42)
      • engineered (62)
      • engineered (66)
      • engineered (94)
    Domains in SCOPe 2.08: d1a94d_
  • Chain 'E':
    Compound: Protease
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03367 (0-98)
      • engineered (6)
      • engineered (32)
      • engineered (42)
      • engineered (62)
      • engineered (66)
      • engineered (94)
    Domains in SCOPe 2.08: d1a94e_
  • Heterogens: 0Q4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a94A (A:)
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwepkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a94B (B:)
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwepkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a94D (D:)
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwepkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a94E (E:)
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwepkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf