PDB entry 1a8m

View 1a8m on RCSB PDB site
Description: tumor necrosis factor alpha, r31d mutant
Class: lymphokine
Keywords: lymphokine, cytokine, cytotoxin
Deposited on 1998-03-27, released 1998-06-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.218
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tumor necrosis factor alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01375 (Start-156)
      • engineered (30)
    Domains in SCOPe 2.07: d1a8ma_
  • Chain 'B':
    Compound: tumor necrosis factor alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01375 (Start-156)
      • engineered (30)
    Domains in SCOPe 2.07: d1a8mb_
  • Chain 'C':
    Compound: tumor necrosis factor alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01375 (Start-156)
      • engineered (30)
    Domains in SCOPe 2.07: d1a8mc_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1a8mA (A:)
vrsssrtpsdkpvahvvanpqaegqlqwlndranallangvelrdnqlvvpseglyliys
qvlfkgqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiyl
ggvfqlekgdrlsaeinrpdyldfaesgqvyfgiial

    Sequence, based on observed residues (ATOM records): (download) 
    >1a8mA (A:)
rtpsdkpvahvvanpqaegqlqwlndranallangvelrdnqlvvpseglyliysqvlfk
gqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiylggvfq
lekgdrlsaeinrpdyldfaesgqvyfgiial

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1a8mB (B:)
vrsssrtpsdkpvahvvanpqaegqlqwlndranallangvelrdnqlvvpseglyliys
qvlfkgqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiyl
ggvfqlekgdrlsaeinrpdyldfaesgqvyfgiial

    Sequence, based on observed residues (ATOM records): (download) 
    >1a8mB (B:)
rtpsdkpvahvvanpqaegqlqwlndranallangvelrdnqlvvpseglyliysqvlfk
gqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiylggvfq
lekgdrlsaeinrpdyldfaesgqvyfgiial

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1a8mC (C:)
vrsssrtpsdkpvahvvanpqaegqlqwlndranallangvelrdnqlvvpseglyliys
qvlfkgqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiyl
ggvfqlekgdrlsaeinrpdyldfaesgqvyfgiial

    Sequence, based on observed residues (ATOM records): (download) 
    >1a8mC (C:)
rtpsdkpvahvvanpqaegqlqwlndranallangvelrdnqlvvpseglyliysqvlfk
gqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiylggvfq
lekgdrlsaeinrpdyldfaesgqvyfgiial