PDB entry 1a8i

View 1a8i on RCSB PDB site
Description: spirohydantoin inhibitor of glycogen phosphorylase
Class: glycogen phosphorylase
Keywords: glycogen phosphorylase, glucopyranose spirohydantoin, water structure, inhibitor binding, anti-hyperglycemic agent
Deposited on 1998-03-25, released 1998-07-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: 0.182
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glycogen phosphorylase b
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00489
      • see remark 999 (379)
      • modified residue (679)
    Domains in SCOPe 2.06: d1a8ia_
  • Heterogens: GLS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1a8iA (A:)
srplsdqekrkqisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvr
dhlvgrwirtqqhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldme
eleeieedaglgngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeead
dwlrygnpwekarpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvnt
mrlwsakapndfnlkdfnvggyiqavldrnlaenisrvlypndnffegkelrlkqeyfvv
aatlqdiirrfksskfgcrdpvrtnfdafpdkvaiqlndthpslaipelmrvlvdlerld
wdkawevtvktcaytnhtvipealerwpvhlletllprhlqiiyeinqrflnrvaaafpg
dvdrlrrmslveegavkrinmahlciagshavngvarihseilkktifkdfyelephkfq
nktngitprrwlvlcnpglaeiiaerigeeyisdldqlrkllsyvddeafirdvakvkqe
nklkfaaylereykvhinpnslfdvqvkriheykrqllnclhvitlynrikkepnkfvvp
rtvmiggkaapgyhmakmiiklitaigdvvnhdpvvgdrlrviflenyrvslaekvipaa
dlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenffifgmrvedvdr
ldqrgynaqeyydripelrqiieqlssgffspkqpdlfkdivnmlmhhdrfkvfadyeey
vkcqervsalyknprewtrmvirniatsgkfssdrtiaqyareiwgvepsrqrlpapdek
ip

    Sequence, based on observed residues (ATOM records): (download) 
    >1a8iA (A:)
qekrkqisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvrdhlvgr
wirtqqhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldmeeleeie
edaglgngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeeaddwlryg
npwekarpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvntmrlwsa
kapngyiqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfksskf
rtnfdafpdkvaiqlndthpslaipelmrvlvdlerldwdkawevtvktcaytnhtvipe
alerwpvhlletllprhlqiiyeinqrflnrvaaafpgdvdrlrrmslveegavkrinma
hlciagshavngvarihseilkktifkdfyelephkfqnktngitprrwlvlcnpglaei
iaerigeeyisdldqlrkllsyvddeafirdvakvkqenklkfaaylereykvhinpnsl
fdvqvkriheykrqllnclhvitlynrikkepnkfvvprtvmiggkaapgyhmakmiikl
itaigdvvnhdpvvgdrlrviflenyrvslaekvipaadlseqistagteasgtgnmkfm
lngaltigtmdganvemaeeageenffifgmrvedvdrldqrgynaqeyydripelrqii
eqlssgffspkqpdlfkdivnmlmhhdrfkvfadyeeyvkcqervsalyknprewtrmvi
rniatsgkfssdrtiaqyareiwgvepsrqrlp