PDB entry 1a61
View 1a61 on RCSB PDB site
Description: thrombin complexed with a beta-mimetic thiazole-containing inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: complex (serine protease-inhibitor), hydrolase-hydrolase inhibitor complex
Deposited on
1998-03-05, released
1998-06-17
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.148
AEROSPACI score: 0.41
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: alpha-thrombin (large subunit)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1a61.1 - Chain 'I':
Compound: hirugen
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: alpha-thrombin (small subunit)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1a61.1 - Heterogens: NA, 00N, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence, based on SEQRES records: (download)
>1a61H (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1a61H (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlkegqpsvlqvvnlpiverpvckdstriritdnmfca
gykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkk
wiqkvidqfg
- Chain 'I':
No sequence available.
- Chain 'L':
Sequence, based on SEQRES records: (download)
>1a61L (L:)
tfgsgeadcglrplfekksledkterellesyidgr
Sequence, based on observed residues (ATOM records): (download)
>1a61L (L:)
adcglrplfekksledkterellesyi