PDB entry 1a52

View 1a52 on RCSB PDB site
Description: estrogen receptor alpha ligand-binding domain complexed to estradiol
Class: receptor
Keywords: receptor, estrogen, ligand, transcription regulation
Deposited on 1998-02-19, released 1998-09-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.223
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • conflict (205)
    Domains in SCOPe 2.08: d1a52a_
  • Chain 'B':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • conflict (205)
    Domains in SCOPe 2.08: d1a52b_
  • Heterogens: EST, AU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1a52A (A:)
mikrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvh
minwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgk
cvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhih
rvldkitdtlihlmakagltlqqqherlaqlllilshirhmsnkgmehlysmkcknvvpl
ydlllemldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >1a52A (A:)
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqherlaqlllilshirhmsnkgmehlysmkcknvvplydllleml

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1a52B (B:)
mikrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvh
minwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgk
cvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhih
rvldkitdtlihlmakagltlqqqherlaqlllilshirhmsnkgmehlysmkcknvvpl
ydlllemldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >1a52B (B:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqherlaqlllilshirhmsnkgmehlysmkcknvvplydllleml