PDB entry 1a36

View 1a36 on RCSB PDB site
Description: topoisomerase I/DNA complex
Class: isomerase/DNA
Keywords: complex (isomerase/DNA), DNA, topoisomerase I
Deposited on 1998-01-29, released 1998-08-12
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.224
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: topoisomerase I
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11387 (Start-590)
      • engineered (548)
    Domains in SCOPe 2.02: d1a36a1, d1a36a2, d1a36a3
  • Chain 'B':
    Compound: DNA (5'-d(*ap*ap*ap*ap*ap*gp*ap*cp*tp*tp*ap*gp*ap*ap*ap*ap*a p*tp*tp*tp*tp*t)- 3')
  • Chain 'C':
    Compound: DNA (5'-d(*ap*ap*ap*ap*ap*tp*tp*tp*tp*tp*cp*tp*ap*ap*gp*tp*c p*tp*tp*tp*tp*t)- 3')
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1a36A (A:)
kpknkdkdkkvpepdnkkkkpkkeeeqkwkwweeerypegikwkflehkgpvfappyepl
penvkfyydgkvmklspkaeevatffakmldheyttkeifrknffkdwrkemtneeknii
tnlskcdftqmsqyfkaqtearkqmskeeklkikeenekllkeygfcimdnhkerianfk
ieppglfrgrgnhpkmgmlkrrimpediiincskdakvpspppghkwkevrhdnkvtwlv
swteniqgsikyimlnpssrikgekdwqkyetarrlkkcvdkirnqyredwkskemkvrq
ravalyfidklalragnekeegetadtvgccslrvehinlhpeldgqeyvvefdflgkds
iryynkvpvekrvfknlqlfmenkqpeddlfdrlntgilnkhlqdlmegltakvfrtyna
sitlqqqlkeltapdenipakilsynranravailcnhqrappktfeksmmnlqtkidak
keqladarrdlksakadakvmkdaktkkvveskkkavqrleeqlmklevqatdreenkqi
algtsklnfldpritvawckkwgvpiekiynktqrekfawaidmadedyef

    Sequence, based on observed residues (ATOM records): (download) 
    >1a36A (A:)
ikwkflehkgpvfappyeplpenvkfyydgkvmklspkaeevatffakmldheyttkeif
rknffkdwrkemtneekniitnlskcdftqmsqyfkaqtearkqmskeeklkikeenekl
lkeygfcimdnhkerianfkieppglfrgrgnhpkmgmlkrrimpediiincskdakvps
pppghkwkevrhdnkvtwlvswteniqgsikyimlnpssrikgekdwqkyetarrlkkcv
dkirnqyredwkskemkvrqravalyfidklalragnekeegetadtvgccslrvehinl
hpeldgqeyvvefdflgkdsiryynkvpvekrvfknlqlfmenkqpeddlfdrlntgiln
khlqdlmegltakvfrtynasitlqqqlkeltapdenipakilsynranravailcnhqe
ksmmnlqtkidakkeqladarrdlksakadakvmkdaktkkvveskkkavqrleeqlmkl
evqatdreenkqialgtsklnfldpritvawckkwgvpiekiynktqrekfawaidmade
dyef

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.