PDB entry 1a2y

View 1a2y on RCSB PDB site
Description: hen egg white lysozyme, d18a mutant, in complex with mouse monoclonal antibody d1.3
Class: complex (immunoglobulin/hydrolase)
Keywords: complex (immunoglobulin/hydrolase), immunoglobulin v region, signal, hydrolase, glycosidase, bacteriolytic enzyme, egg white
Deposited on 1998-01-13, released 1998-04-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.203
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: igg1-kappa d1.3 fv (light chain)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01635 (0-106)
      • conflict (2)
      • conflict (49-51)
      • conflict (95)
    Domains in SCOPe 2.08: d1a2ya_
  • Chain 'B':
    Compound: igg1-kappa d1.3 fv (heavy chain)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01820 (0-95)
      • conflict (4)
      • conflict (55)
      • conflict (85)
    Domains in SCOPe 2.08: d1a2yb_
  • Chain 'C':
    Compound: lysozyme
    Species: Gallus gallus [TaxId:9031]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00698 (0-128)
      • engineered (17)
    Domains in SCOPe 2.08: d1a2yc_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1a2yA (A:)
    divltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvyytttladgvps
    rfsgsgsgtqyslkinslqpedfgsyycqhfwstprtfgggtkleik
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1a2yB (B:)
    qvqlqesgpglvapsqslsitctvsgfsltgygvnwvrqppgkglewlgmiwgdgntdyn
    salksrlsiskdnsksqvflkmnslhtddtaryycarerdyrldywgqgttltvss
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1a2yC (C:)
    kvfgrcelaaamkrhglanyrgyslgnwvcaakfesnfntqatnrntdgstdygilqins
    rwwcndgrtpgsrnlcnipcsallssditasvncakkivsdgngmnawvawrnrckgtdv
    qawirgcrl