PDB entry 1a2c
View 1a2c on RCSB PDB site
Description: Structure of thrombin inhibited by AERUGINOSIN298-A from a BLUE-GREEN ALGA
Class: Hydrolase/Hydrolase Inhibitor
Keywords: HYDROLASE, SERINE PROTEASE, Hydrolase-Hydrolase Inhibitor complex
Deposited on
1997-12-26, released
1998-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-06-05, with a file datestamp of
2013-05-31.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.15
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: Thrombin heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1a2c.1 - Chain 'I':
Compound: Hirudin variant-2
Species: Hirudo medicinalis [TaxId:6421]
Database cross-references and differences (RAF-indexed):
- Chain 'J':
Compound: Aeruginosin 298-A
Species: Microcystis aeruginosa [TaxId:1126]
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: Thrombin light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1a2c.1 - Heterogens: NA, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence, based on SEQRES records: (download)
>1a2cH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1a2cH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketgqpsvlqvvnlpiverpvckdstriritdnmfc
agykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlk
kwiqkvidqfge
- Chain 'I':
No sequence available.
- Chain 'J':
No sequence available.
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>1a2cL (L:)
tfgsgeadcglrplfekksledkterellesyidgr