PDB entry 1a27

View 1a27 on RCSB PDB site
Description: human 17-beta-hydroxysteroid-dehydrogenase type 1 c-terminal deletion mutant complexed with estradiol and nadp+
Class: dehydrogenase
Keywords: dehydrogenase, 17-beta-hydroxysteroid, mutant, estradiol, nadp
Deposited on 1998-01-16, released 1998-05-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-04-11, with a file datestamp of 2018-04-06.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 17-beta-hydroxysteroid-dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1a27a_
  • Heterogens: EST, NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1a27A (A:)
    artvvlitgcssgiglhlavrlasdpsqsfkvyatlrdlktqgrlweaaralacppgsle
    tlqldvrdsksvaaarervtegrvdvlvcnaglgllgplealgedavasvldvnvvgtvr
    mlqaflpdmkrrgsgrvlvtgsvgglmglpfndvycaskfaleglceslavlllpfgvhl
    sliecgpvhtafmekvlgspeevldrtdihtfhrfyqylahskqvfreaaqnpeevaevf
    ltalrapkptlryftterflpllrmrlddpsgsnyvtamhrevfgdvpa
    

    Sequence, based on observed residues (ATOM records): (download)
    >1a27A (A:)
    artvvlitgcssgiglhlavrlasdpsqsfkvyatlrdlktqgrlweaaralacppgsle
    tlqldvrdsksvaaarervtegrvdvlvcnaglgllgplealgedavasvldvnvvgtvr
    mlqaflpdmkrrgsgrvlvtgsvgglmglpfndvycaskfaleglceslavlllpfgvhl
    sliecgpvhtafmekvlgspeevldrtdihtfhrfyqylahskqvfreaaqnpeevaevf
    ltalrapkptlryftterflpllrmrlddpsgsnyvtamhrevfg