PDB entry 1a0h

View 1a0h on RCSB PDB site
Description: the x-ray crystal structure of ppack-meizothrombin desf1: kringle/thrombin and carbohydrate/kringle/thrombin interactions and location of the linker chain
Class: hydrolase/hydrolase inhibitor
Keywords: serine protease, coagulation, thrombin, prothrombin, meizothrombin, hydrolase-hydrolase inhibitor complex
Deposited on 1997-11-30, released 1998-06-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-09.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: meizothrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00735 (0-158)
      • conflict (23)
    Domains in SCOPe 2.08: d1a0h.1, d1a0ha1
  • Chain 'B':
    Compound: meizothrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1a0h.1
  • Chain 'D':
    Compound: meizothrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00735 (0-158)
      • conflict (23)
    Domains in SCOPe 2.08: d1a0h.2, d1a0hd1
  • Chain 'E':
    Compound: meizothrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1a0h.2
  • Heterogens: 0G6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a0hA (A:)
splletcvpdrgreyrgrlavtthgsrclawsseqakalskdqdfnpavplaenfcrnpd
gdeegawcyvadqpgdfeycdlnyceepvdgdlgdrlgedpdpdaaiegrtsedhfqpff
nektfgageadcglrplfekkqvqdqtekelfesyiegr

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a0hB (B:)
ivegqdaevglspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftvddll
vrigkhsrtryerkvekismldkiyihprynwkenldrdiallklkrpielsdyihpvcl
pdkqtaakllhagfkgrvtgwgnrretwttsvaevqpsvlqvvnlplverpvckastrir
itdnmfcagykpgegkrgdacegdsggpfvmkspynnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidrlgs

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a0hD (D:)
splletcvpdrgreyrgrlavtthgsrclawsseqakalskdqdfnpavplaenfcrnpd
gdeegawcyvadqpgdfeycdlnyceepvdgdlgdrlgedpdpdaaiegrtsedhfqpff
nektfgageadcglrplfekkqvqdqtekelfesyiegr

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1a0hE (E:)
ivegqdaevglspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftvddll
vrigkhsrtryerkvekismldkiyihprynwkenldrdiallklkrpielsdyihpvcl
pdkqtaakllhagfkgrvtgwgnrretwttsvaevqpsvlqvvnlplverpvckastrir
itdnmfcagykpgegkrgdacegdsggpfvmkspynnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidrlgs