PDB entry 173d

View 173d on RCSB PDB site
Description: multiple binding modes of anticancer drug actinomycin d: x-ray, molecular modeling, and spectroscopic studies of d(gaagcttc)2- actinomycin d complexes and its host dna
Deposited on 1994-04-18, released 1994-10-15
The last revision was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA (5'-d(*gp*ap*ap*gp*cp*tp*tp*c)-3')
  • Chain 'B':
    Compound: DNA (5'-d(*gp*ap*ap*gp*cp*tp*tp*c)-3')
  • Chain 'C':
    Compound: actinomycin d
    Species: Streptomyces antibioticus [TaxId:1890]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00228 (0-End)
  • Chain 'D':
    Compound: actinomycin d
    Species: Streptomyces antibioticus [TaxId:1890]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00228 (Start-10)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records:
    >173dC (C:)
tvpgvxtvpgv

    Sequence, based on observed residues (ATOM records):
    >173dC (C:)
tvpgvx

  • Chain 'D':
    Sequence, based on SEQRES records:
    >173dD (D:)
tvpgvxtvpgv

    Sequence, based on observed residues (ATOM records):
    >173dD (D:)
xtvpgv