Original-Style Sequences 2.03

  • Explanation: A SCOPe domain may include fragments from different PDB chains (see d1cph.1, for example). A genetic domain is a SCOPe domain in which the fragments are concatenated in the order in which they appear in the original gene or sequence. In the original-style Astral SCOPe sequence sets, there is a separate entry for each chain (the section of d1cph.1 in chain A: becomes e1cph.1a, and the part in chain B: becomes e1cph.1b). In the genetic domain sequence sets, there is a single entry, g1cph.1, in which the sequences for chains B: and A: appear in the correct order, separated by the letter 'X'.
    Genetic domain sequences are now the default.

  • If you don't want original-style sequences, click here for the genetic domain (standard) sequences.

    Most commonly requested files:

    • Astral SCOPe 2.03 original-style sequence subsets, based on PDB SEQRES records,
      with less than 40% identity to each other: download sequences (3.2 MB)
    • Astral SCOPe 2.03 original-style sequence subsets, based on PDB SEQRES records,
      with less than 95% identity to each other: download sequences (6 MB)

  • All Astral SCOPe original-style sequences, based on PDB SEQRES records: download sequences (46 MB)

  • All Astral SCOPe original-style sequences, based on PDB ATOM records: download sequences (45.6 MB)
    These are not recommended unless you have a special need.

  • Percentage identity-filtered Astral SCOPe original-style sequence subsets, based on PDB SEQRES records.
    with less than percent identity (using "in both" criterion).

  • E-value filtered Astral SCOPe original-style sequence subsets, based on PDB SEQRES records.
    with E-values >= (in a database size of 100,000,000 residues).

  • SCOPe filtered Astral SCOPe original-style sequence subsets, based on PDB SEQRES records.
    that represent each in SCOPe.