SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Superfamily b.179.1: PA14-like

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2078445Fold b.179: Anthrax protective antigen N-terminal-like [254104] (1 superfamily)
    core: sandwich; 10-12 strands in 2 sheets; jelly roll; may contain inserted subdomains
  4. 2078446Superfamily b.179.1: PA14-like [254123] (3 families) (S)

Families:

  1. 2078447b.179.1.1: PA14 [254147] (2 protein domains)
    Pfam PF07691
  2. 2078488b.179.1.2: GLEYA domain [254187] (2 protein domains)
    Pfam PF10528
    PubMed 21149680; inserted Flo5 subdomain (84-120) contains 5 short beta strands and two disulfide bridges
  3. 2078514b.179.1.0: automated matches [254312] (1 protein)
    not a true family

More info for Superfamily b.179.1: PA14-like

Timeline for Superfamily b.179.1: PA14-like: